高分子材料作为生物活性药物缓释载体的化学与物理结构研究进展

Journal of Macromolecular Science-reviews in Macromolecular Chemistry and Physics Pub Date : 1983-01-01 DOI:10.1080/07366578308079439

R. Langer, N. Peppas

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引用次数: 370

摘要

在控释系统中，药物、农药或其他生物活性剂被掺入载体，通常是聚合物材料。该物质的释放速率由聚合物本身的特性决定，对环境因素(如体液的pH值)的依赖性较弱。控制释放系统能够缓慢而连续地递送物质长达数年。

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Chemical and Physical Structure of Polymers as Carriers for Controlled Release of Bioactive Agents: A Review

Abstract In a controlled release system a drug, pesticide, or other bio-active agent is incorporated into a carrier, generally a polymeric material. The rate of release of the substance is determined by the properties of the polymer itself and is only weakly dependent on environmental factors (such as the pH of bodily fluids). Controlled release systems are capable of delivering substances slowly and continuously for up to several years.

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Journal of Macromolecular Science-reviews in Macromolecular Chemistry and Physics

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