埃塞俄比亚南部Wolkite镇公共卫生中心孕妇处方药使用的流行率和决定因素

B. Zeleke, Zebene Mekonnen, Meskele Bireda, Melaku Yitbarek
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引用次数: 0

摘要

背景:孕妇因治疗原因不小心使用药物可能导致发育中的胎儿严重的功能和结构损害。本研究的目的是确定埃塞俄比亚南部古拉格地区公共卫生中心孕妇处方药使用的患病率及其相关因素。方法:对孕妇进行基于机构的横断面研究。通过使用标准数据收集工具从患者图表和采访孕妇中收集数据。采用SPSS 23.0版本对数据进行分析,采用多项logistic回归模型估计不同研究变量之间的相关性。p值<0.05认为有统计学意义。结果:在418例孕妇中,约91.1%的孕妇至少服用过一种药物,平均每张处方的药物数量为2.4种。合并并发症的孕妇AOR = 19.66, 95% CI(8.747 ~ 44.218), 1次就诊AOR = 2.787 95% CI(1.265 ~ 6.142), 2次就诊AOR =2.704(1.042 ~ 7.018),原发期患者AOR = 3.553 95% CI(1.644 ~ 7.680)使用处方药物(硫酸亚铁除外)的可能性增加1倍。结论:沃尔凯特镇公共卫生中心孕妇妊娠期处方用药的发生率较高,但根据FDA风险分级标准,大部分用药均为适宜、安全用药。合并症的存在、妊娠和首次到卫生设施就诊的时间与怀孕期间处方药物的使用显著相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and Determinants of Prescribed Drug Use Among Pregnant Women at Public Health Center in Wolkite Town, Southern Ethiopia
: Background : Incautious utilization of drugs by pregnant women for therapeutic reasons may result in severe functional and structural damages in the developing fetus. The objective of this study was to determine the prevalence and associated factors of prescribed drug use among pregnant women at public health center in Gurage Zone, Southern Ethiopia. Methods : Institution based cross sectional study was conducted on pregnant women. Data was collected from patient charts and interviewing pregnant women by using standard data collection tools. The data was analyzed using SPSS version 23.0 and multinomial logistic regression model was utilized estimate association across different study variables. P-values <0.05 were considered statistically significant. Results : Of a total of 418 pregnant women, about 91.1% were prescribed with at least one medication and there were an average 2.4 numbers of drugs per a prescription. Pregnant women with comorbidity were AOR = 19.66, 95% CI (8.747-44.218), who visited the health facility once were AOR = 2.787 95% CI (1.265-6.142) and twice were AOR =2.704 (1.042-7.018), and with primigravida were AOR = 3.553 95% CI (1.644-7.680) times more likely to use prescribed drugs (except ferrous sulphate). Conclusion : Although majority of the drugs used was appropriate and safe medications according to FDA risk classification system, the prevalence of prescribed medication use during pregnancy is very high in public health center of Wolkite town. Presence of comorbidity, gravidity and time of first visits to health facilities were significantly associated with prescribed drug use during pregnancy.
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