乔斯地区骨髓抽吸细胞学检查所需贫血的流行病学

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
O. Egesie, D. Joseph, U. Egesie, O. Ewuga
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引用次数: 26

摘要

目的:探讨、鉴别和分类我国环境中需要骨髓穿刺细胞学检查的各种贫血病因。方法:对2005年1月1日至2008年12月31日期间因贫血而转诊到乔斯大学教学医院血液学和输血科的患者的所有骨髓穿刺细胞学报告进行回顾性审查。结果:最常见的贫血原因是急性白血病(n=45: 24.3%);其次是巨幼细胞合并缺铁性贫血(营养缺乏性贫血)(n=34: 18.4%);骨髓衰竭(再生障碍性贫血)(n= 20:10.8%)。仅骨髓抽吸细胞学检查未能确定少数患者贫血的原因(n=6: 3.2%)。结论:该研究为我们了解环境中贫血的原因提供了有价值的见解。与普遍认为缺铁是贫血最常见的原因相反,在这种环境下,急性白血病被发现是贫血最常见的原因,其次是营养因子缺乏和骨髓衰竭。缺乏实验室设施阻碍了在这种环境下对贫血病因的进一步调查。应更加强调确定和管理贫血的具体原因,而不是目前的基础广泛的管理方法。由于早期诊断对血液病的总体结果有积极影响,因此有必要向公众宣传早期就诊和彻底检查的必要性。尼日尔医学杂志,第50卷,第3期,2009年7 - 9月:61 - 63。关键词:贫血,骨髓穿刺细胞学,流行病学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiology of Anaemia Necesitating Bone Marrow Aspiration Cytology in Jos
Objective: The study aims at investigating, identifying and classifying the various causes of anaemia necessitating bone marrow aspiration cytology in our environment. Methodology: A retrospective review of all bone marrow aspiration cytology reports of patients referred to Haematology and Blood Transfusion department of the Jos University Teaching Hospital between January 1st 2005 and December 31st 2008 on account of anaemia was carried out. Results: The commonest cause of anaemia was acute leukaemia (n=45: 24.3%); followed by combined megaloblastic and iron deficiency anaemia (nutritional deficiency anaemia) (n=34: 18.4%); and bone marrow failure (Aplastic anaemia) (n=20: 10.8%). Bone marrow aspiration cytology alone failed to identify causes of anaemia in a few patients (n=6: 3.2%). Conclusion: The study provides a valuable insight into the causes of anaemia in our environment. In contrast to the general opinion that iron deficiency is the commonest cause of anaemia, acute leukaemia was found to be the commonest cause of anaemia in this environment followed by deficiency of nutritional factors and bone marrow failure. Lack of laboratory facilities has hindered further investigation of causes of anaemia in this environment. More emphasis should be placed on identifying and managing the specific cause of anaemia rather than the current broad based approach to management. Public enlightenment on the need for early presentation to hospital and thorough investigations is necessary as early diagnosis affects positively the overall outcome of haematological diseases. Niger Med J. Vol. 50, No. 3, July – Sept., 2009: 61 – 63. Key words: anaemia, bone marrow aspiration cytology, epidemiology.
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来源期刊
Nigerian Postgraduate Medical Journal
Nigerian Postgraduate Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.90
自引率
0.00%
发文量
52
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