Dopant ions’ behavior in solution synthesis of substituted calcium phosphates

The dependence of the (Zn, Cu, Co, Ni, Mn)-substituted calcium phosphates’ composition on the water synthesis method has been studied. Cation-substituted tricalcium phosphates and hydroxyapatites were obtained by precipitation from an aqueous solution and by the mechanical activation’ method. The reaction products were dried, calcined at 400°C and investigated by ICP AES and flame AAS. The content of Zn, Cu, Co, Ni, Mn in samples and mother liquors was quantitatively determined. It has been established that the content of Cu2+, Zn2+, Co2+, Ni2+ ions in phosphates is greatly reduced compared to the calculated amounts. At the same time, for tricalcium phosphate, precipitation and the mechanical activation’ method gave comparable results for the content of dopant ions. At the same time, the mechanical activation’ method increase the content of the dopant ion in the substituted hydroxyapatites up to ≈ 48 %.