姜黄(Curcuma longa)的民族医药、植物化学和抗病毒潜力

Compounds Pub Date : 2022-08-26 DOI:10.3390/compounds2030017
B. B. Srivastava, A. Ripanda, Hossein Miraji Mwanga
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引用次数: 8

摘要

自史前以来,姜黄(Curcuma longa)一直是一种著名的根茎作物,具有药用价值。大多数病毒性疾病缺乏有效的治疗方法,一些抗病毒治疗费用较高,以及出现抗病毒药物耐药性的报道越来越多。预计到2050年,耐药性将成为全球死亡的主要原因,因此需要进行干预。需要有效的天然抗病毒化合物来减轻病毒性疾病,如姜黄素,这需要进一步的研究。姜黄素是一种主要的姜黄素类化合物,已被证明具有广泛的抗病毒活性。由于需要克服对化学合成药物的耐药性,最好的选择是改进和适应天然抗病毒药物的使用。姜黄素的抗病毒潜力受到其溶解度和生物利用度的阻碍。近年来,姜黄素碳量子点的制备等技术被用于提高姜黄素的抗病毒活性。因此,本综述旨在评价姜黄素作为一种天然抗病毒药物的益处和提高其药用活性的技术。未来姜黄素的使用将有助于减轻病毒性疾病,包括耐药菌株,因此整个社区的可持续性。在这种情况下,需要进行研究和创新,以提高姜黄素的溶解度和生物利用度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ethnomedicinal, Phytochemistry and Antiviral Potential of Turmeric (Curcuma longa)
Turmeric (Curcuma longa) has been a famous root crop for its medicinal properties since pre-historical times. Lack of effective therapeutics for most viral diseases, higher cost of some antiviral therapies, and the emergence of antiviral drug resistance are increasingly reported. Drug resistance is predicted to be a leading cause of mortality globally by 2050, thus requiring intervention. The need for effective natural antiviral compounds to mitigate viral diseases, such as curcumin, calls for further studies. Curcumin, a primary curcuminoid compound, has demonstrated a broad activity as an antiviral agent. Due to the need to overcome drug resistance to chemically synthesised drugs, the best option is to improve and adapt the use of natural antiviral agents. The antiviral potential of curcumin is hindered by its solubility and bioavailability. Recently, different techniques, such as the preparation of curcumin carbon quantum dots, have been used to improve curcumin antiviral activity. Therefore, the current review aims to assess curcumin’s benefits as a natural antiviral agent and techniques to improve its medicinal activity. Future use of curcumin will aid in mitigating viral diseases, including resistant strain, hence sustainability of the entire community. In this case, research and innovation are required to improve the solubility and bioavailability of curcumin for medical uses.
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CiteScore
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