麦卢卡蜂蜜与湿与干敷料对开放毛窦手术后伤口愈合时间的影响

H. Abtar, J. Terro, E. El-helou, K. Jammoul, Ryan Said Lakkis, N. Ismail, M. Al-Raishouni, Charbel Aoun
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摘要

背景:骶尾骨毛突窦疾病是一种非常常见的先天性裂慢性炎症,通常表现为脓肿。治疗需要根除窦道和术后伤口护理。麦卢卡蜂蜜(Medihoney)用于急性和慢性伤口。在我们的研究中,我们试图研究麦卢卡蜂蜜在减少伤口切除后愈合时间方面的临床效果。材料和方法:我们使用传统的描述性统计来描述患者的特征。我们通过Kaplan-Meier分析比较了接受Medihoney治疗和未接受Medihoney治疗的患者的研究终点(伤口愈合时间)。结果:2017年至2018年,共有119例患者接受了毛囊囊肿手术。Medihoney组的中位愈合时间为40天,而对照组为39天。在调整年龄、BMI、创面长度、创面体积、吸烟情况和手术时间等因素后,治疗组的愈合时间明显少于未治疗组(风险比1.56,95%可信区间1.02 ~ 2.49,p= 0.041)。结论:术后使用麦卢卡蜂蜜与纱布敷料相比,伤口愈合时间明显缩短。进一步的研究将有助于探索这种敷料技术的最佳治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Manuka Honey Versus Wet to Dry Dressing for Wound Closure Time After Open Pilonidal Sinus Surgery
Background: Sacrococcygeal pilonidal sinus disease is a very common chronic inflammation of the natal cleft that presents frequently as an abscess. Management requires the eradication of the sinus tract and postoperative wound care. Manuka honey (Medihoney) was used in acute and chronic wounds. In our study, we sought to investigate the clinical effectiveness of Manuka honey in decreasing wound healing time post excision. Material and Methods: We describe patients’ characteristics using traditional descriptive statistics. We compared the study endpoint (wound closure time) in patients who received Medihoney versus those who did not by Kaplan-Meier analysis. Results: A total of 119 patients underwent pilonidal cyst surgery between the years 2017 and 2018. The median time for healing in the Medihoney group was 40 days compared with 39 days in the control group. After adjusting for age, BMI, wound length, wound volume, smoking and operative time, the time to healing in the Medihoney group was significantly less compared to the group not receiving the treatment (Hazard Ratio 1.56, 95% Confidence interval 1.02- 2.49, p= 0.041). Conclusion: Postoperative use of Manuka honey showed a significant decrease in wound healing time when compared to gauze fabric dressings. Further research would be beneficial to explore optimal treatment protocols for this dressing technique.
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