极早产儿和极低出生体重儿的肠系膜上动脉血流及其相关因素

IF 0.2 Q4 PEDIATRICS

Paediatrica Indonesiana Pub Date : 2023-04-06 DOI:10.14238/pi63.2.2023.80-7

Evita B. Ifran, Wresti Indriatmi, Tetty Yuniarti, Nadjib Advani, S. Sungkar, Dewi Irawati Soeria Santoso, R. Rohsiswatmo, Y. Vandenplas, B. Hegar

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引用次数: 0

摘要

背景:早产儿在生命早期显著的血流动力学变化可能会产生后果，特别是对肠道血流。肠系膜上动脉(SMA)血流的改变可能导致肠道功能受损和喂养不耐受。目的评价极早产儿和/或极低出生体重儿(VLBW)早期SMA血流速度及其影响因素。方法本研究是在雅加达Cipto Mangunkusumo医院NICU进行的横断面研究。出生后< 48小时，采用彩色多普勒超声测量收缩期峰值速度(PSV)、舒张末期速度(EDV)和阻力指数(RI)，评估肠系膜上动脉(SMA)血流。获得了可能与SMA血流相关的孕产妇和新生儿数据。进行双变量分析，P值< 0.05认为显著。结果我们检查了156名符合研究条件的婴儿。SMA血流量PSV、EDV和RI与胎龄和出生体重无关。与适宜胎龄(AGA)相比，小胎龄婴儿(SGA)的EDV中位数明显较低[15.5(范围0-32.8)vs 19.4(范围0-113.0)]，RI较高[0.80(范围0.58-1.00)vs 0.78(范围0.50-1.00)]。与没有PE相比，母亲患有先兆子痫的婴儿的PSV中位数[(78.2(范围32.0-163.0)vs 89.7(范围29.2-357.0)]和EDV[16.2(范围0.0-48.5)vs 19.4(范围0.0-113.0)]较低，而缺失/反向舒张末期速度(AREDV)显示，与没有AREDV相比，EDV中位数[16.9(范围0.0- 32.4)vs 19.4(范围0.0-113.0)]较低。此外，与非hs-PDA相比，患有hs-PDA的婴儿的EDV中位数较低[16.2(范围0.0-113.0)vs 19.4(范围0.0-71.1)]，但RI中位数较高[0.80(范围0.50-1.00)vs 0.78(范围0.55-1.00)]。其他因素对SMA血流量没有影响。

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Superior mesenteric artery blood flow in infants of very preterm and very low birthweight and its related factors

Abstract Background Significant hemodynamic changes in preterm infants during early life could have consequences, especially on the intestinal blood flow. Alteration of superior mesenteric artery (SMA) blood flow may lead to impairment in gut function and feeding intolerance. Objectives To assess SMA blood flow velocity in very preterm and/or very low birth weight (VLBW) infants in early life and to elucidate the factors influencing them. Methods This is a cross-sectional study conducted in NICU at Cipto Mangunkusumo Hospital, Jakarta. Superior mesenteric artery (SMA) blood flow was evaluated by peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index (RI) measurement using Color Doppler US at < 48 hours after birth. Maternal and neonatal data that could be potentially associated with SMA blood flow were obtained. Bivariate analyses were conducted with a P value of < 0.05 considered significant. Results We examined 156 infants eligible for the study. PSV, EDV, and RI of SMA blood flow were not related to both gestational age and birth weight. Infant with small for gestational age (SGA) showed significantly lower EDV median [15.5 (range 0.0-32.8) vs 19.4 (range 0.0-113.0)] and higher RI [0.80 (range 0.58-1.00) vs 0.78 (range 0.50-1.00)] compared to appropriate for gestational age (AGA). Infants born from mother with preeclampsia showed lower PSV median [(78.2 (range 32.0-163.0) vs 89.7 (range 29.2-357.0)]) and EDV [16.2 (range 0.0-48.5) vs 19.4 (range 0.0-113.0)] compared to without PE, while absent/reverse end-diastolic velocity (AREDV) revealed a lower EDV median [16.9 (range 0.0 – 32.4) vs 19.4 (range 0.0 – 113.0)] compared to no AREDV. Furthermore, infants with hs-PDA showed lower EDV median [16.2 (range 0.0-113.0) vs 19.4 (range 0.0-71.1)] but higher RI median [0.80 (range 0.50-1.00) vs 0.78 (range 0.55-1.00)] compared to non hs-PDA. No difference in SMA blood flow across other factors was observed.

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来源期刊

Paediatrica Indonesiana PEDIATRICS-

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

24 weeks