真性红细胞增多症并发颧弓骨折1例

R.S.G. Satyasai, Prasanna Patruni, Nagasai K Nagasai K, Sravani P Sravani P, Meghana V Meghana V, Divya P Divya P
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摘要

真性红细胞增多症(PV)是一种骨髓增殖性肿瘤疾病,其特征是红细胞(rbc)合成不正常。巨核细胞和髓系经常同时受到刺激;这会导致白细胞和血小板合成的增加。因此,血栓形成和出血的风险增加。由于面部和下颌有广泛的血管网络,手术止血的途径有限,创伤性损伤和外科手术是失血增加的最常见原因之一。颧骨骨折是面部骨骼最常见的骨折之一。颧骨是一块坚固的骨头,支撑着上颌骨和颅底。然而,它的突出使它极易受到影响,特别是当面部两侧受到冲击时。面部骨折与1-11%的失血过多有关。这些并发症有可能显著增加围手术期的发病率和死亡率。在治疗这些患者时必须采取充分的预防措施以获得成功的结果。PV患者的治疗包括术前静脉切开术、增加液体摄入和抗血小板治疗。本报告展示了一个复杂的程序的管理,如颌面创伤的PV患者的正常凝血特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of Zygomatic Arch Fracture in Polycythemia Vera Patient-A Case Report
Polycythemia vera (PV) is a myeloproliferative neoplastic condition characterized by an unregulated synthesis of red blood cells (RBCs). There is often simultaneous stimulation of the megakaryocytic and myeloid lineages; this causes an increase in the synthesis of white blood cells and platelets2. As a result, there is an increased risk of thrombosis and bleeding. Due to the extensive vascular network of the face and jaw7 and limited surgical access to perform hemostasis, traumatic injuries and surgical procedures are among the most common causes of increased blood loss. Zygomatic bone fracture is one of the most frequent fractures of the facial skeleton. The zygomatic bone is a strong bone that supports the maxilla and the skull base. However, its prominence makes it highly susceptible, mainly when impact occurs on both sides of the face4. Facial bone fractures are associated with 1–11% excess blood loss. These complications have the potential to increase perioperative morbidity and mortality significantly. Adequate precautions must be taken in treating these patients for successful outcomes. The management of patients with PV includes therapeutic preoperative phlebotomy, increased fluid intake, and antiplatelet therapy. This report demonstrates the management of a complex procedure such as maxillofacial trauma in a PV patient with a normal coagulation profile.
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