{"title":"真核生物转录的分子基础研究。罗杰·科恩伯格获2006年诺贝尔化学奖","authors":"O. P. Matyshvska","doi":"10.15407/ubj94.04.093","DOIUrl":null,"url":null,"abstract":"The Nobel Prize in Chemistry 2006 was awarded to an American biochemist and professor of structural biology at Stanford University Roger Kornberg for his fundamental research on the molecular mechanisms of copying genetic information in eukaryotic cells. What are these molecular mechanisms? How is transcription complex formed and what is its structure? R. Kornberg devoted tirelessly 20 years of his work to answer these questions. The article is focused on his research and also describes Roger Kornberg’s life and scientific career. Keywords: DNA, protein crystals, RNA, RNA polymerase II, Roger Kornberg, transcription, transcription complex","PeriodicalId":23007,"journal":{"name":"The Ukrainian Biochemical Journal","volume":"36 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Studies of the molecular basis of eukaryotic transcription. Roger Kornberg the Nobel prize in Chemistry 2006\",\"authors\":\"O. P. Matyshvska\",\"doi\":\"10.15407/ubj94.04.093\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The Nobel Prize in Chemistry 2006 was awarded to an American biochemist and professor of structural biology at Stanford University Roger Kornberg for his fundamental research on the molecular mechanisms of copying genetic information in eukaryotic cells. What are these molecular mechanisms? How is transcription complex formed and what is its structure? R. Kornberg devoted tirelessly 20 years of his work to answer these questions. The article is focused on his research and also describes Roger Kornberg’s life and scientific career. Keywords: DNA, protein crystals, RNA, RNA polymerase II, Roger Kornberg, transcription, transcription complex\",\"PeriodicalId\":23007,\"journal\":{\"name\":\"The Ukrainian Biochemical Journal\",\"volume\":\"36 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Ukrainian Biochemical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15407/ubj94.04.093\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Ukrainian Biochemical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15407/ubj94.04.093","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
2006年诺贝尔化学奖被授予美国生物化学家、斯坦福大学结构生物学教授罗杰·科恩伯格(Roger Kornberg),以表彰他在真核细胞中复制遗传信息的分子机制方面的基础研究。这些分子机制是什么?转录复合体是如何形成的,它的结构是什么?R. Kornberg不知疲倦地投入了20年的工作来回答这些问题。这篇文章的重点是他的研究,也描述了罗杰·科恩伯格的生活和科学生涯。关键词:DNA,蛋白质晶体,RNA, RNA聚合酶II, Roger Kornberg,转录,转录复合物
Studies of the molecular basis of eukaryotic transcription. Roger Kornberg the Nobel prize in Chemistry 2006
The Nobel Prize in Chemistry 2006 was awarded to an American biochemist and professor of structural biology at Stanford University Roger Kornberg for his fundamental research on the molecular mechanisms of copying genetic information in eukaryotic cells. What are these molecular mechanisms? How is transcription complex formed and what is its structure? R. Kornberg devoted tirelessly 20 years of his work to answer these questions. The article is focused on his research and also describes Roger Kornberg’s life and scientific career. Keywords: DNA, protein crystals, RNA, RNA polymerase II, Roger Kornberg, transcription, transcription complex