未听风险:考虑侵入性认知在复发中的作用

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
A. Doonan, T. Buchanan
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引用次数: 0

摘要

物质使用障碍(SUD)是一种普遍和持续的公共卫生危机,每年造成许多人死亡和住院。尽管经过数十年的研究,我们仍未开发出一种有效的跨物质治疗模式。许多寻求并接受SUD治疗的人最终都复发了,尽管他们的意图是这样的。治疗成功的不一致性需要在SUD的潜在核心机制中识别新的,通用的治疗靶点。确定促进成瘾行为的认知机制是充分了解SUD复发和维持的重要第一步。本综述的目的是探讨治疗后延长SUD的潜在认知过程。通过这一点,我们提出了一种机制模型,说明侵入性认知如何通过风险决策危及症状改善和SUD治疗的成功。侵入性认知——图像、文字、记忆或冲动——几乎不需要认知上的努力,而且有助于快速采取行动和做出决定。在这篇论文中,我们提供的证据表明,侵入性认知如果受到不良抑制,可能会损害SUD的决策过程,并导致随后的成瘾行为。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unheard risk: considering the role of intrusive cognitions in relapse
Abstract Substance use disorders (SUD) represent a pervasive and ongoing public health crisis responsible for many deaths and hospitalizations each year. Despite decades of research, we have yet to develop an effective cross-substance treatment model. Many who seek and enter treatment for SUD end up relapsing despite their intentions. Inconsistency in treatment success necessitates the identification of novel, universal therapeutic targets in the underlying core mechanisms of SUD. Determining the cognitive mechanisms which promote addictive behaviors is an essential first step to fully understand relapse and maintenance in SUD. The goal of the current review is to explore underlying cognitive processes which prolong SUD despite treatment. Through this, we propose a mechanistic model for how intrusive cognitions may jeopardize symptom improvement and SUD treatment success via risky decision making. Intrusive cognitions - images, words, memories, or impulses - demand little cognitive effort, and lend themselves to quick action and decisions. In the current paper, we present evidence which shows how intrusive cognitions, poorly inhibited, could impair the decision making process in SUD and lead to subsequent addictive behaviors.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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