利用在线太赫兹传感技术研究药片在穿孔包衣机内的混合过程

Xiaoran Li, P. Bawuah, Bryan M. Williams, J. Zeitler, Hungyen Lin
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引用次数: 0

摘要

在线太赫兹传感已被证明可以在包衣过程中测量单个药物片的包衣厚度。由于涂布均匀性高度依赖于片剂的混合,本研究展示了我们迄今为止使用在线太赫兹传感来研究挡板设计、滚筒转速和批次大小对实验室大小的穿孔盘式涂布机内片剂混合的影响的研究进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Studying pharmaceutical tablets mixing process inside a perforated pan-coater using in-line terahertz sensing
In-line terahertz sensing has been demonstrated to measure the coating thickness of individual pharmaceutical tablets during coating operation. As coating uniformity is highly dependent on tablet mixing, this study presents our research progress to date on using in-line terahertz sensing to investigate the effects of baffle design, drum rotational speed and batch size, on tablet mixing inside a laboratory-sized perforated pan coater.
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