Julio Benites, Holbert D. Asunción-Alvarez, Roberto O. Ybañez-Julca, Mayar L. Ganoza-Yupanqui, Juan J. Jacinto-Fernandez, Junior B. Reyes-De la Vega, Hair J. Zavaleta-Cruz, Adela N. Pinedo-Alcántara, Cristian M. Lavado-Fonseca, Carlos A. Medina-Mejia, M. Catalán, Bernardo Morales, R. D. D. G. D. Albuquerque, Leandro Rocha, José L. Martínez
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引用次数: 0
摘要
芒果的化学成分。采用HPLC-ESI-QTOF-MS/MS对“Kent”叶片进行测定。以二苯甲酮衍生物为主要成分的多酚类化合物(1、大柳苷3-C-(2- o -没食子酰)- d -葡萄糖苷异构体;2、maclurin 3-C-——d -葡萄糖苷;3、环氟苯酮3- c -——d -葡萄糖苷;5、maclurin 3-C-(2,3-二- o -没食子酰)-- d -葡萄糖苷;6、环氟苯酮3-C-(2- o -没食子酰)-- d -葡萄糖苷;7、甲基环氟苯酮3-C-(2,6-二- o -没食子酰基)-- d -葡萄糖苷)和山酮(4,6 - o -没食子酰基芒果苷和8,6 - o -没食子酰基芒果苷)。芒果水提物的雌激素和抗氧化作用。采用子宫营养测定法和红细胞、骨、肝、胃中丙二醛(MDA)水平测定去卵巢大鼠的“肯特”叶。我们得出结论，从提取物中提取的多酚类化合物作为外源性抗氧化剂对卵巢切除大鼠的氧化损伤起作用。
Composición química por HPLC-ESI-QTOF-MS/MS: efectos estrogénicos y antioxidantes de extractos de Mangifera indica L. cv. “Kent” en ratas ovariectomizadas
The chemical composition of Mangifera indica L. cv. "Kent" leaves was determined by HPLC-ESI-QTOF-MS/MS. Polyphenolic compounds characterized as benzophenone derivatives were the main components found in extracts (1, maclurin 3-C-(2-O-galloyl)-D-glucoside isomer; 2, maclurin 3-C---D-glucoside; 3, iriflophenone 3-C---D-glucoside; 5, maclurin 3-C-(2,3-di-O-galloyl)---D-glucoside; 6, iriflophenone 3-C-(2-O-galloyl)---D-glucoside; 7, methyl-iriflophenone 3-C-(2,6-di-O-galloyl)---D-glucoside) and xanthones (4, mangiferin and 8, 6-O-galloyl-mangiferin). The estrogenic and antioxidant effects of aqueous extracts from Mangifera indica L. cv. "Kent" leaves on ovariectomized rats were determined by uterotrophic assay and malondialdehyde (MDA) levels in erythrocytes, bone, liver, and stomach. We conclude that the polyphenolic compounds from extracts act as exogenous antioxidant agents against oxidative damage in ovariectomized rats.
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