生物化学方法:采用静态顶空气相色谱-质谱法同时测定环境和人体生物基质中的甲醛和甲基叔丁基醚

A. M. Beigi, M. Shamsipur
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引用次数: 8

摘要

本文介绍了一种基于静态顶空萃取(HS) -气相色谱/质谱(GC/MS)的人体血液和水样中甲基叔丁基醚(MTBE)和甲醛(HCHO)的定性和定量分析方法。细胞色素P4502A6对MTBE转化为叔丁醇(TBA)和HCHO具有重要作用。为提高萃取效果,对萃取温度、萃取时间、顶空体积比、氯化钠浓度等萃取参数进行了优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biochemistry Method: Simultaneous determination of formaldehyde and methyl tert-buthyl ether in environmental and human biological matrices using static headspace gas chromatography mass spectrometry
The present study describes a method based on static headspace- extraction (HS) followed by gas chromatography/ mass spectrometry (GC/MS) for the qualitative and quantitative analysis of Methyl tert-buthyl ether (MTBE) and formaldehyde (HCHO) in human blood and water samples. Cytochrome P4502A6 has important role for converting of MTBE to tert-butyl alcohol (TBA) and HCHO. To enhance the extraction capability of the HS, extraction parameters such as extraction temperature, extraction time, the ratio of headspace volume to sample volume and sodium chloride concentration have been optimized.
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CiteScore
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