捷克共和国的空气污染和可能的痴呆风险

IF 2.5 3区工程技术 Q2 BIOLOGY

Yale Journal of Biology and Medicine Pub Date : 2022-10-15 DOI:10.17352/jbm.000031

J. Topinka, P. Rossner, A. Rossnerova, R. Sram

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引用次数: 0

摘要

对最近文献的回顾表明，空气污染对痴呆症，特别是阿尔茨海默病发病率的增加有显著影响。一个可能的机制与氧化损伤和炎症有关。在捷克共和国，在过去的几十年里，北波希米亚矿区的空气污染程度非常高，而在上一个时期，北摩拉维亚也注意到这个问题。这一特殊情况可用于研究空气污染对痴呆症的影响，使用分子流行病学的新方法，并对生活在污染地区的人口的生活方式进行复杂分析。

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Air pollution and possible risk of dementia in the Czech Republic

A review of recent literature indicates a significant effect of air pollution on the increased incidence of dementia, particularly Alzheimer’s disease. A possible mechanism is related to oxidative damage and inflammation. In the Czech Republic in previous decades the mining districts of Northern Bohemia suffered from very high air pollution levels, while during the last period in Northern Moravia this problem was also noted. This specific situation could be used to study the impact of air pollution on dementia, using new methods of molecular epidemiology together with the complex analysis of the lifestyle of the population living in the polluted regions.

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来源期刊

Yale Journal of Biology and Medicine Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology

CiteScore

5.00

自引率

0.00%

发文量

期刊介绍： The Yale Journal of Biology and Medicine (YJBM) is a graduate and medical student-run, peer-reviewed, open-access journal dedicated to the publication of original research articles, scientific reviews, articles on medical history, personal perspectives on medicine, policy analyses, case reports, and symposia related to biomedical matters. YJBM is published quarterly and aims to publish articles of interest to both physicians and scientists. YJBM is and has been an internationally distributed journal with a long history of landmark articles. Our contributors feature a notable list of philosophers, statesmen, scientists, and physicians, including Ernst Cassirer, Harvey Cushing, Rene Dubos, Edward Kennedy, Donald Seldin, and Jack Strominger. Our Editorial Board consists of students and faculty members from Yale School of Medicine and Yale University Graduate School of Arts & Sciences. All manuscripts submitted to YJBM are first evaluated on the basis of scientific quality, originality, appropriateness, contribution to the field, and style. Suitable manuscripts are then subject to rigorous, fair, and rapid peer review.