Delirious Mania: Recognition and Successful Treatment with Donepezil

Aims: Presentation of a case of severe delirious mania with resolution of delirium after treatment with donepezil. Presentation of Case: KA was a 44 y/o Australian female with a history of bipolar affective disorder with psychotic manic episodes. Two weeks prior to her psychiatric admission she was admitted to a medical ward after an overdose (OD) of acetaminophen. On review, it appeared that pathological processes involved in delirium may require unique and individual recognition and management. Conclusion: This case suggests that the use of donepezil is strongly recommended in the treatment of delirious mania. Further study is required to clarify in this challenging disorder.