心脏手术中主动脉内球囊泵植入后的预后用新评分计算

H. Hausmann, E. Potapov, A. Koster, T. Krabatsch, J. Stein, R. Yeter, M. Kukucka, R. Sodian, H. Kuppe, R. Hetzer
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引用次数: 95

摘要

背景:在过去的十年中,心室辅助装置(VAD)用于心切术后心源性休克患者的出院率为25%至40%,并且正在改善。然而,对于接受了主动脉内球囊泵(IABP)的患者,VAD植入的适应症和时机仍不清楚。方法与结果对1996年7月至2000年3月391例经心内直视手术植入IABP的心脏低排血量综合征患者进行回顾性初步研究。围手术期死亡率为34%(133例)。在IABP支持开始1小时后分析临床参数。多因素统计分析显示,肾上腺素需求高于0.5 μ g·kg - 1·min - 1、左房压>15 mm Hg、尿量<100 mL/h、混合静脉饱和度(SvO2) <60%的患者预后较差。利用这些数据,我们开发了IABP评分(0到5分)来预测心脏手术中IABP植入后的早期生存。我们通过监测另外101名患者作为前瞻性对照组来评估我们的评分。此外,我们还分析了210例接受冠状动脉旁路移植术(CABG)的患者。所有的调查都证实了分数的有效性。结论IABP评分可预测IABP植入术后早期患者的生存。对于IABP评分较高的患者,应考虑植入VAD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prognosis After the Implantation of an Intra-Aortic Balloon Pump in Cardiac Surgery Calculated With a New Score
BackgroundOver the past decade, the use of a ventricular-assist device (VAD) in patients with postcardiotomy cardiogenic shock has resulted in hospital discharge rates of 25% to 40% and is improving. Nevertheless, indications for and timing of the implantation of a VAD in patients who have received an intra-aortic balloon pump (IABP) remain unclear. Methods and ResultsFrom July 1996 to March 2000, 391 patients with cardiac low-output syndrome who underwent open-heart surgery and had an IABP implanted were analyzed in a retrospective pilot study. The perioperative mortality was 34% (133 patients). Clinical parameters were analyzed 1 hour after IABP support began. Statistical multivariate analysis showed that patients with an adrenaline requirement higher than 0.5 &mgr;g · kg−1 · min−1, a left atrial pressure >15 mm Hg, urine output <100 mL/h, and mixed venous saturation (SvO2) <60% had poor outcomes. Using this data, we developed an IABP score (0 to 5 points) to predict survival early after IABP implantation in cardiac surgery. We evaluated our score by monitoring another 101 patients as a control group prospectively. Additionally, 210 patients who received coronary artery bypass grafting (CABG) exclusively were analyzed. All investigations confirmed the validity of the score. ConclusionsThe IABP score can predict survival early after IABP implantation. In patients with a high IABP score, implantation of a VAD should be considered.
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