Circulating magnesium & Acute phage inflammatory reactant in North Indian adult population

Background: The increase of several serum proteins named acute phase reactants is a feature of the tissue response to inflammation . C-reactive protein (CRP) is one of the most sensitive acute-phase reactants in humans. Magnesium is found to be associated with these inflammatory reactants in previous studies. Objectives: The aim of this study was to investigate the relationship between serum magnesium levels and C- reactive protein in apparently healthy adults. Methods and material: This is a population based cross-sectional study. Total 130 adults of age between 25-65 years, were recruited with prior ethical approval and with written informed consent. Result: Mean value of serum magnesium was found to be 2.01mg/dl (±0.29) with range between 1.4mg/dl to 2.9mg/dl. Not a single case of severe hypomagnesemia (< 1.2 mg/dl) was found. Serum magnesium was found to have no significant correlation with C-reactive protein (r = -0.12, p=0.23). Conclusion: Authors report no significant co-relation between serum magnesium and CRP. Further larger studies are required to be done.