左旋肉碱对高脂饲养褐家鼠精子质量和睾酮激素的影响试验

N. Antari, I. Damayanti, Nadya Tressna Wulansari
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引用次数: 8

摘要

本研究旨在测定给褐家鼠(Rattus norvegicus)左旋肉碱后精子质量和睾丸激素的增加情况。本研究采用左旋肉碱治疗大鼠42天,剂量分别为100 mg/kg bw、150 mg/kg bw和200 mg/kg bw,并与对照组进行比较。本研究中观察到的变量是精子的质量,即:形态、活力、活力、膜完整性和睾酮激素水平。研究数据使用计算机统计程序(SPSS 22.0 for Windows)处理,采用单因素方差分析检验。结果表明,长期服用高剂量的左旋肉碱补充剂会导致精子质量下降,即:形态、活力、活力、膜完整性和激素睾酮水平下降。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
effectiveness testing of l-carnitine on the quality of spermatozoa and testosterone hormone in white rats (Rattus norvegicus) feeding with high fat
This study aims to determine the increase in the quality of spermatozoa and testosterone after giving L-carnitine to white rats (Rattus norvegicus). This study was conducted by giving L-carnitine as a treatment for 42 days in white rats with a dose variation of 100 mg/kg bw, 150 mg/kg bw, and 200 mg/kg bw and user controls as a comparison. The variables observed in this study were the quality of spermatozoa, namely: morphology, motility, viability, membrane integrity, and seeing the levels of the hormone testosterone. The research data were processed using a computer statistical program (SPSS 22.0 for Windows) using the One Way Anova test. The results showed that giving high doses of L-carnitine supplements for a long time could cause decreased spermatozoa quality, namely: morphology, motility, viability, membrane integrity and decreased levels of the hormone testosterone.
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