Clinical manifestations of central sensitization in patients with episodic migraine combined with active cervicalgic component

The article considers the relation between clinical manifestations of central sensitization (CS) and the course of episodic migraine as an independent nosology and combined with cervicalgia or cervicogenic headache. The research objective was to study the comorbid pathologies in patients with episodic migraine, characteristic for central sensitization — anxiety, depression, cervicalgia, cervicogenic headache, and sleep disorders. We found the relationship between the intensity of migraine pain syndrome, migraine duration in anamnesis, and the central sensitization index — CSI. At the same time, the CS intensity also directly depended on the number of involved muscles and triggers. The effect was shown of the cervicogenic factor as a predictor or trigger in patients with migraine and cervicogenic headache, as well as the significant impact of clinical manifestations of CS on the quality of life of patients with episodic migraine.