促性腺激素对母羊卵泡生长的控制。

A. S. McNeilly, H. Picton, B. K. Campbell, D. T. Baird
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引用次数: 96

摘要

母羊的排卵前卵泡生长依赖于卵泡刺激素,尽管血浆卵泡刺激素浓度与排卵前卵泡数量或排卵率之间似乎没有确切的关系。这可能与迄今为止尚未认识到的脉动性LH对大卵泡生长的影响有关。排卵前卵泡的生长依赖于基础黄体生成素的存在,但脉动性黄体生成素虽然对增加卵泡颗粒细胞的雄激素底物至关重要,但也可能在降低许多大卵泡对卵泡刺激素的反应性中起作用,特别是在排卵前阶段,当血浆中卵泡刺激素浓度降低时。因此,排卵前卵泡的选择可能涉及到先前未被认识到的FSH和脉动性LH分泌之间的相互作用,其中LH脉冲以消极而不是积极的方式起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gonadotrophic control of follicle growth in the ewe.
Preovulatory follicle growth in the ewe is dependent on FSH although no precise relationship appears to exist between plasma concentrations of FSH and the number of preovulatory follicles which develop or ovulation rate. This may be related to a hitherto unrecognized influence of pulsatile LH on the growth of large follicles. Preovulatory follicle growth is dependent on the presence of basal amounts of LH, but pulsatile LH, while being essential to supply an increase in androgen substrate to the granulosa cells of the follicle, may also play a role in reducing the responsiveness of many large follicles to FSH, in particular during the preovulatory phase when plasma concentrations of FSH are reduced. Thus selection of the preovulatory follicle(s) may involve a previously unrecognized interaction between FSH and pulsatile LH secretion in which pulses of LH act in a negative rather than positive manner.
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