核苷-切除修复(NER)通路在软组织肉瘤中的作用:综述及其作为治疗靶点的潜力

Cancer studies and therapeutics Pub Date : 2023-08-18 DOI:10.31038/cst.2023824

Pillozzi Serena, Scolari Federico, Pasqui Adriano, Boddi Anna, Fancelli Sara, Caliman Enrico, Palchetti Ilaria, Bernini Andrea, Petroni Giulia, Scoccianti Guido, Campanacci Domenico, Antonuzzo Lorenzo

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摘要

软组织肉瘤(STS)是一种低发病率的间质源性肿瘤，有50多种类型。尽管有了最新的进展，但患者发生复发和转移性疾病的比率仍然很高。STS的许多机制尚不清楚

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The Role of the Nucleotide-Excision Repair (NER) Pathway in Soft Tissue Sarcomas: A Review and a Focus on Its Potential as a Therapeutic Target

Soft tissue sarcomas (STS) are low-incidence, mesenchymal-derived tumors represented by more than 50 his to types. Despite the latest developments, the rates of patients developing recurrent and metastatic disease are high. Many of the mechanisms underlying STS are still unknown

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Cancer studies and therapeutics

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