用umu试验研究原型银银、瓷键合和含铟金银钯合金的突变性

Journal of oral tissue engineering Pub Date : 2015-01-01 DOI:10.11223/JARDE.13.27

K. Imai, T. Nishikawa, Tomoharu Okamura, A. Tanaka, Tatsuro Miyake, I. Tamura, Hiroki Ishikawa, T. Iseki, S. Morita, H. Sawai, T. Ohkubo, M. Shida, K. Suese

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引用次数: 0

摘要

有许多诱变剂会增加生物制品DNA和染色体遗传信息突变的频率。在致癌物中，大多数引起遗传信息异常并引起癌症的起始物是诱变剂。许多牙科合金包括在国家健康保险和临床使用，如银和金银钯合金。然而，铟及其化合物的毒性已被报道，世界卫生组织提出了使用umu试验研究含铟原型银银、瓷键合和金银钯合金的致突变性的可能性

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Study of the Mutagenicity of Prototype Ag-In, Porcelain Bonding and Au-Ag-Pd Alloys Containing Indium using the Umu-test

27 INTRODUCTION There are many mutagens which increase the frequency of mutation in DNA and chromosomal genetic information of biologics. Of carcinogens, most of the initiators that produce an abnormality in genetic information and a cause of cancer are mutagens . Many dental alloys are covered by national health insurance and clinically used, such as Ag-In and gold-silver-palladium alloys . However, the toxicity of indium and its compounds has been reported , and the WHO stated the possibility of the Study of the Mutagenicity of Prototype Ag-In, Porcelain Bonding and Au-Ag-Pd Alloys Containing Indium using the Umu-test

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Journal of oral tissue engineering

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