sglt -2抑制剂在心力衰竭中的应用

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引用次数: 1

摘要

心力衰竭是一种常见且高度衰弱的病理。血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂、β受体阻滞剂、矿皮质激素受体拮抗剂和缬沙坦/沙比利已被证明可以降低慢性心力衰竭患者的死亡率,同时降低射血分数。最近,格列嗪(SGLT‐2抑制剂)已成为伴有射血分数降低的心力衰竭的另一种有效治疗选择,适用于伴有或不伴有糖尿病的患者。本文综述了SGLT‐2抑制剂对心血管系统和心力衰竭的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SGLT-2-Inhibitors in Heart Failure
Heart failure is a frequent and highly debilitating pathology. Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers, β‐ blockers, mineralocorticoid receptor antagonists, and valsartan/sacubitril have been shown to reduce mortality in chronic heart failure with reduced ejection fraction. Recently, glifozines (SGLT‐2 inhibitors) have become another effective therapeutic option for heart failure with reduced ejection fraction, in patients with and without diabetes mellitus. The review presents the effects of SGLT‐2 inhibitors on the cardiovascular system and heart failure.
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