B细胞耗竭疗法作为中枢神经系统脱髓鞘疾病的前沿治疗方法

Q3 Multidisciplinary

Annals of Clinical and Experimental Neurology Pub Date : 2023-06-21 DOI:10.54101/acen.2023.2.9

T. Simaniv, A. Belkina, M. Zakharova

{"title":"B细胞耗竭疗法作为中枢神经系统脱髓鞘疾病的前沿治疗方法","authors":"T. Simaniv, A. Belkina, M. Zakharova","doi":"10.54101/acen.2023.2.9","DOIUrl":null,"url":null,"abstract":"Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the disease progression and help maintain patients' quality of life and social participation. We analyzed pathogenic mechanisms of multiple sclerosis and other B cell-mediated diseases and reviewed therapeutic options for main disease stages.","PeriodicalId":36946,"journal":{"name":"Annals of Clinical and Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"B Cell Depletion Therapy as a Cutting-Edge Treatment of Demyelinating Diseases of the Central Nervous System\",\"authors\":\"T. Simaniv, A. Belkina, M. Zakharova\",\"doi\":\"10.54101/acen.2023.2.9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the disease progression and help maintain patients' quality of life and social participation. We analyzed pathogenic mechanisms of multiple sclerosis and other B cell-mediated diseases and reviewed therapeutic options for main disease stages.\",\"PeriodicalId\":36946,\"journal\":{\"name\":\"Annals of Clinical and Experimental Neurology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Clinical and Experimental Neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54101/acen.2023.2.9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Multidisciplinary\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Clinical and Experimental Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54101/acen.2023.2.9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Multidisciplinary","Score":null,"Total":0}

引用次数: 0

摘要

特别是中枢神经系统脱髓鞘疾病和多发性硬化症是医学界和整个社会迫切需要解决的问题。开发和实施高效的特异性治疗可显著减缓疾病进展，并有助于维持患者的生活质量和社会参与。我们分析了多发性硬化症和其他B细胞介导疾病的致病机制，并对主要疾病分期的治疗方案进行了综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

B Cell Depletion Therapy as a Cutting-Edge Treatment of Demyelinating Diseases of the Central Nervous System

Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the disease progression and help maintain patients' quality of life and social participation. We analyzed pathogenic mechanisms of multiple sclerosis and other B cell-mediated diseases and reviewed therapeutic options for main disease stages.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Annals of Clinical and Experimental Neurology Medicine-Neurology (clinical)

CiteScore

0.80

自引率

0.00%

发文量