C. Plainvert, Yasmina de Saint Salvy-Tabet, N. Dmytruk, A. Frigo, C. Poyart, Asmaa Tazi
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引用次数: 0
摘要
B群链球菌(GBS)是新生儿感染的主要原因，也是妊娠期的重要病原体。然而，妊娠相关感染的特征报道很少。我们分析了336例18至50岁女性的GBS侵袭性感染，其中242例(72.0%)为妊娠相关感染。妊娠期以羊膜内感染为主(55.8%)，发生早产(61.3%)，伴有产科和新生儿并发症(81.7%)。GBS克隆CC-17(18.8%的病例)在产时被过度代表(35.2%;Or = 5.1, 95% ci 1.6-19.3)。这项工作强调了妊娠期间GBS和CC-17克隆感染的负担。
Group B Streptococcus invasive infections in women of childbearing age, France, 2012 - 2020 : GBS CC-17 hypervirulence in intrapartum infections.
Group B Streptococcus (GBS) is the leading cause of neonatal infections and an important pathogen in pregnancy. However, the features of pregnancy-associated infections are poorly reported. We analyzed 336 cases of GBS invasive infections in women aged 18 to 50 years old, including 242 (72.0%) pregnancy-associated infections. In pregnancy, most cases were intra-amniotic infections (55.8%), occurred preterm (61.3%) and were associated to obstetrical and neonatal complications (81.7%). The GBS clone CC-17 (18.8% of the cases) was overrepresented intrapartum (35.2%; OR = 5.1, 95% CI 1.6-19.3). This work highlights the burden of GBS and of the CC-17 clone infections during pregnancy.
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