在利比亚班加西Sidi-Hussein健康中心,用光学相干断层成像定量测量糖尿病对中央黄斑厚度的影响

Mervat A. Omear, S. Bukhatwa, Fatma Benkhaial
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摘要

糖尿病性黄斑水肿(DME)是糖尿病性视网膜病变(DR)中视力下降最常见的原因,其检测需要设备和技术。光学相干断层扫描(OCT)是一种能够测量视网膜形态学特征的客观技术,有助于提高诊断和治疗水平。目的:本研究通过与临床眼底检查的比较,评估OCT黄斑在糖尿病患者DME筛查中的作用,同时评估OCT黄斑测量的中央黄斑厚度(CMT)与患者视力的关系。环境和设计:2014年至2017年期间在班加西Sidi Hussein健康中心进行了一项回顾性研究。对象与方法:对393例(786只眼)II型糖尿病患者资料进行回顾性分析。除眼底检查记录(非接触+90屈光度晶状体)外,提取病例特征记录。评估OCT (CMT)记录与主观眼底检查的一致性以及与其他措施的关系。数据以频率表示,统计分析使用statistical Package for the Social Science (Windows version 17.0;SPSS Inc., USA)。结果:经OCT诊断为轻度DME的眼中,约537眼(82%)主观上无DR。经OCT检查,轻度DME患者555只眼(85%)视力良好(最小角度分辨率0.3及以下的对数)。重度DME患者约10只眼(71%)糖尿病持续时间为10 ~ 20年。结论:OCT是一种无创的方法,可以在DME影响患者视力之前客观地检测和量化早期DME,强烈建议将其作为利比亚患者检测和筛查DME的首选技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of diabetes on central macular thickness quantitatively measured using optical coherence tomography at Sidi-Hussein Health Center, Benghazi, Libya
Introduction: Diabetic macular edema (DME) is the most common cause of decreased vision in diabetic retinopathy (DR) and its detection needs equipment and skills. Optical coherence tomography (OCT) is an objective technique that can measure retinal morphologic characteristic which help improving diagnosis and treatment. Aims: This study was conducted to evaluate the role of OCT macula in the screening for DME in patients with diabetes by comparing it to clinical funduscopy in addition to assessing the relationship between central macular thickness (CMT) as measured by OCT macula and the visual acuity of patient. Settings and Design: A retrospective study was done at Sidi Hussein Health center/Benghazi in the period between 2014 and 2017. Subjects and Methods: The data of 393 (786 eyes) patients with diabetes (type II) were reviewed. Cases characteristics records were extracted in addition to fundus examination records (done by noncontact +90-diopter lens). The records of OCT (CMT) were evaluated for agreement with the subjective fundus examination and in relation to other measures. Data were presented as frequencies and the statistical analyses were performed using Statistical Package for the Social Science (Windows version 17.0; SPSS Inc., USA). Results: Around 537 eyes (82%) of eyes with mild DME as diagnosed by OCT were having no DR when examined subjectively. With OCT, it was found that 555 eyes (85%) with mild DME were having good visual acuity (logarithm of the minimum angle of resolution 0.3 and less). About 10 eyes (71%) having severe DME were having duration of diabetes of 10–20 years. Conclusions: OCT is a noninvasive method that can objectively detect and quantify early DME before it affects the vision of patients and it is strongly recommended that this should be the technique of choice for detecting and screening of DME in Libyan patients.
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