ILC2s是肠道IL-10来源的主要来源

The Tokushima journal of experimental medicine Pub Date : 2019-11-07 DOI:10.1084/jem.20191520

Jennifer K. Bando, S. Gilfillan, B. Di Luccia, J. L. Fachi, Cristiane Sécca, M. Cella, M. Colonna

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引用次数: 78

摘要

这项研究表明，在四种不同设施中饲养的小鼠中不存在调节性先天淋巴细胞(ILCreg)，这是一种最近被描述的产生il -10的先天淋巴细胞。相反，2组IL-10在肠道中提供了诱导源。

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ILC2s are the predominant source of intestinal ILC-derived IL-10

This study shows that the regulatory innate lymphoid cell (ILCreg), a recently described IL-10–producing innate lymphocyte, is not present in mice bred in four different facilities. Instead, group 2 ILCs provide an inducible source of IL-10 in the intestine.

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The Tokushima journal of experimental medicine

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