ABO血型与Covid-19感染关系的评价

IF 0.3 4区医学 Q4 ONCOLOGY

Uhod-Uluslararasi Hematoloji-Onkoloji Dergisi Pub Date : 2020-09-30 DOI:10.4999/UHOD.204348

S. Aktimur, A. Şen, B. Yazıcıoğlu, A. Gunes, S. Genç

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引用次数: 7

摘要

新型冠状病毒病2019 (COVID-19)正在全球迅速蔓延，世卫组织已宣布疫情爆发。血型对COVID-19感染和疾病严重程度的影响尚不清楚。本研究的目的是确定ABO血型与COVID-19感染易感性之间的关系，以及血型是否将成为COVID-19感染的生物标志物。本研究纳入了2020年3月至5月诊断为SARS-CoV-2的患者，以便将患者的血型与健康组进行比较。在2020年2月至5月期间曾在血库进行ABO血型分析的患者被纳入对照组人口统计数据、临床数据、潜在合并症、实验室检查结果和临床结果(住院、需要重症监护、死亡率)从电子病历获得总共179例患者确认COVID-19患者和5200名健康控制COVID-19患者被纳入研究显示一个分布在A组的62 01%,B组9 50%,8 94%组AB和19 55%组O在A组,在重症监护室的长度更长(10 42±11 61天;p = 0 013)相比,健康对照组的血型,COVID-19患者的A血型高于健康组(62% vs 46.6%;p 0.001)， O血型低于健康组(19.6% vs 34.7%;p 0.001) A血型可作为COVID-19疾病的预测性生物标志物。此外，我们得出结论，A组患COVID-19疾病的风险和严重程度更高©2020,UHOD - Uluslararasi Hematoloji Onkoloji Dergisi版权所有

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The Assessment of the Relationship Between ABO Blood Groups and Covid-19 Infection

The new coronavirus disease-2019 (COVID-19) is rapidly spreading around the world and has been declared an outbreak by WHO However, the effect of blood groups on COVID-19 infection and the severity of the disease is unclear The aim of this study is to determine the relationship between ABO blood group and susceptibility to COVID-19 infection and whether the blood group will be a biomarker for COVID-19 infection Patients diagnosed with SARS-CoV-2 between March and May 2020 were included in this study In order to compare the blood groups of the patients with the healthy group, patients who had previously performed ABO blood group analysis in the blood bank between February and May 2020 were included as the control group Demographic data, clinical data, underlying comorbidities, laboratory findings and clinical results (hospitalization, need for intensive care, mortality) were obtained from the electronic medical records A total of 179 patients with confirmed COVID-19 and 5200 healthy control patients were included in the study Patients with COVID-19 showed a distribution of 62 01% in group A,9 50% in group B, 8 94% in group AB and 19 55% in group O In group A, length of stay in Intensive Care Unit was longer (10 42±11 61 days;p= 0 013) Compared to the blood groups of the healthy control group, COVID-19 patients had higher A blood group than the healthy group (62& vs 46 6%;p 0 001) and lesser of the O blood group (19 6% vs 34 7%;p 0 001) Blood group A can be used as a predictive biomarker for COVID-19 disease In addition, we concluded that the group A had a higher risk for COVID-19 disease and severity © 2020, UHOD - Uluslararasi Hematoloji Onkoloji Dergisi All rights reserved

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来源期刊

Uhod-Uluslararasi Hematoloji-Onkoloji Dergisi ONCOLOGY-

CiteScore

1.60

自引率

16.70%

发文量

审稿时长

>12 weeks

期刊介绍： Target of Publication is the public representation of new scientific results of fundamental, problem-oriented, and search scientific investigations; analytical articles and reviews by actual scientific problems of coal mining industry, short reports in the field of coal mining industry, including the results of work of scientific meetings, conferences, summit’s and congresses in the field of mining. The basic purpose of the journal is the promotion of innovative activity in the coal mining industry by highlighting and discussing the results of basic and applied research, the experience in applying results of innovation for the development of the Russian coal mining. The most important tasks of the journal are: the generalization of scientific and practical achievements of specialists in the field of coal mining industry, specializing in the implementation of promising basic and applied research and development of priorities of high technologies; the scientific concept of the publication; the publication of the latest achievements in the field of innovation in coal mining industry. The journal lays special emphasis on methodical elaborations, analytical investigations in the sphere of coal mining. Targets of Journal are in publication of new results of scientific investigations performed by scientists, post-graduate students, and doctoral candidates performed by from higher schools, Russian Academy of Sciences, other scientific organizations of Russia, CIS countries, and foreign universities