Clinical research of femtosecond laser mushroom incision penetrating corneal transplantation combined cataract extraction

Objective To evaluate the effectiveness and safety of mushroom incision femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery. Methods A retrospective analysis was carried out for 29 patients (30 eyes) who performed FS- PKP combined cataract extracapsular extraction versus 11 patients (11 eyes) who performed traditional PKP combined cataract extracapsular extraction. Lesions involving whole cornea and all the patients’ lenticular opacity were moderate or above. Femtosecond laser was used for make mushroom incision of corneal graft and corresponding recipient bed, conventional group used trephine. Then implemented cataract extracapsular extraction, intraocular lens were implanted, sutured at last. Their follow-up were 1 week, 1 month, 3 months and 6 months, part of the patient were followed up until 18 months. The follow-up results of two groups were compared. Results Postoperative vision of two groups had increased, postoperative UCVA and BCVA of femtosecond group were better than normal group, postoperative astigmatism was lower than normal group within 3 months, and there was no obvious difference after 6 months. No obvious difference was found between two groups of ECD and postoperative complications occurrence rate. Conclusions Mushroom incision of femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery has obvious curative effect, precision cutting and high security, its early visual acuity is superior to the traditional penetrating keratoplasty, it can be widely used in clinical therapy. Key words: Femtosecond laser; Keratoplasty; Cataract; Penetrating; Leukoma