当与局部非手术牙周治疗联合使用时,抗菌光动力疗法或全身抗生素对改善牙周健康更有效吗?系统回顾

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
A. Pal, Sanjeev Paul, R. Perry, J. Puryer
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引用次数: 12

摘要

牙周病有几种治疗方法。本文综述了抗菌素光动力疗法(aPDT)加刮治和刨根(SRP)是否比全身抗生素(ABs)联合SRP治疗牙周炎患者的临床效果更好。使用以下电子数据库检索研究:MEDLINE、Cochrane系统评价数据库和Web of Science核心合集,截止至2018年11月。我们回顾了四项随机对照试验(rct),以最大限度地提高证据的可靠性。所有参与者都患有慢性或侵袭性牙周炎,每个研究都包含SRP作为ABs或aPDT的辅助药物。为了确定各组治疗后是否有改善,选择的结局参数是探探深度(PD)、临床附着水平(CAL)和探探出血(BOP)。尽管发现所有组都有显著的改善,但组间的差异在统计学上并不一致。缺乏同质性在这些研究结果表明,它是不可能确定一个结论是否aPDT或AB作为兼职SRP牙周炎以提供更好的改善PD,卡尔和防喷器。在得出确定的结论之前,需要进行更多类似研究设计的进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review
Periodontal disease can be treated in several ways. This paper reviewed whether antimicrobial photodynamic therapy (aPDT) in addition to scaling and root planing (SRP) produces improved clinical results over systemic antibiotics (ABs) in conjunction with SRP in adults with periodontitis. Studies were searched using the following electronic databases: MEDLINE, the Cochrane Database of Systematic Reviews, and the Web of Science Core Collection up to and including November 2018. Four randomized controlled trials (RCTs) were reviewed to maximise the reliability of the evidence. All participants suffered from either chronic or aggressive periodontitis and each study contained SRP as an adjunct to ABs or aPDT. To determine whether groups showed improvement after treatment, the outcome parameters chosen were probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP). Despite finding significant improvements in all groups, the differences among groups were not consistently statistically significant. The lack of homogeneity in the results among these studies indicates that it was not possible to determine a conclusion about whether aPDT or AB as an adjunct to SRP provides better improvements in periodontitis as measured by PD, CAL, and BOP. Further studies with more similar study designs are required before firm conclusions can be deduced.
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来源期刊
Open Dentistry Journal
Open Dentistry Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
2.00
自引率
0.00%
发文量
86
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