非危及生命疾病的药物发现:勃起功能障碍、失眠和戒烟

Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2010-09-15 DOI:10.1002/0471266949.BMC200

D. Rotella

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摘要

非危及生命疾病的药物发现是药物化学研究的一个活跃领域。本章将描述用于勃起功能障碍的磷酸二酯酶5抑制剂的发现和性质，治疗失眠和戒烟的药物化学。关键词:失眠;磷酸二酯酶5抑制剂;戒烟

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Drug Discovery in Non‐Life‐Threatening Disorders: Erectile Dysfunction, Insomnia, and Smoking Cessation

Drug discovery for non-life-threatening disorders is an active area of medicinal chemistry research. This chapter will describe the discovery and properties of phosphodiesterase 5 inhibitors for erectile dysfunction, the medicinal chemistry of agents for treatment of insomnia, and smoking cessation. Keywords: insomnia; phosphodiesterase 5 inhibitors; smoking cessation

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Burger's Medicinal Chemistry and Drug Discovery

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