在断奶期间引起的已愈合动脉炎的过早动脉粥样硬化

Journal of Applied Clinical Pediatrics Pub Date : 2000-02-05 DOI:10.3969/J.ISSN.1003-515X.2000.01.002

Liu Ya-li, H. Xiao-hua

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引用次数: 1

摘要

目的探讨川崎病远期冠状动脉硬化发生的危险性.方法实验分为两组:A组用马血清诱发兔的动脉炎,3mo后加用含5%胆固醇饲料喂养;B组未诱发动脉炎,饲料喂养同A组,5mo时两组取心脏做HE和马森染色,观察冠状动脉的病理组织学变化,IBAS画像解析装置测算.结果A组冠状动脉主干部内膜的肥厚、纤维性硬化以及心肌内冠状动脉的硬化程度均比B组明显(P＜0.05).结论动脉炎后冠状动脉内膜的隐匿性病变使患病血管比正常血管更易诱发动脉硬化.

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Premature atherogensis in the healed arteritis induced during the weaning period

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Journal of Applied Clinical Pediatrics

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