通过热成像技术评估鼻烟中尼古丁的口服吸收对外周皮肤血液循环的影响。

Temperature: Multidisciplinary Biomedical Journal Pub Date : 2014-11-17 eCollection Date: 2014-10-01 DOI:10.4161/23328940.2014.984553
Ina Isabella Høiland, Louis de Weerd, James B Mercer
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引用次数: 0

摘要

吸烟对健康的危害众所周知,但对使用无烟烟草(ST)对健康的危害却知之甚少。本研究旨在评估以口服含尼古丁的鼻烟和不含尼古丁的鼻烟形式使用无烟烟草对外周皮肤血液循环的影响。21 名习惯吸食含尼古丁鼻烟的年轻人参加了这项研究。在受控条件下,受试者分别口服含尼古丁的鼻烟(SN+)和不含尼古丁的鼻烟(SN-)30 分钟。通过红外热成像技术测量手部皮肤温度,间接监测手部皮肤血液循环。据统计,在 SN+ 实验中,手部皮肤血液循环显著下降,而在 SN- 实验中,皮肤血液循环几乎不受影响。结论是,以口服含尼古丁鼻烟的形式使用无烟烟草会导致外周皮肤血液循环下降,而不含尼古丁的鼻烟则不会产生这种影响。这些知识可能会在治疗需要充足的外周皮肤血液循环的病人时,或在军人暴露在寒冷条件下时派上用场。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of oral uptake of nicotine in snus on peripheral skin blood circulation evaluated by thermography.

While health risks from smoking cigarettes are well known, little is known about the health risks of using smokeless tobacco (ST). The aim of this study was to evaluate the effect that ST in the form of oral use of snus with nicotine and snus without nicotine has on peripheral skin blood circulation. 21 young habitual users of snus with nicotine participated in this study. Under controlled conditions the subjects were exposed to a 30 minute period of oral use of snus with nicotine (SN+) and snus without nicotine (SN-). The peripheral skin blood circulation was indirectly monitored on the hands by measuring skin temperature using infrared thermography. The skin blood circulation in the hands showed a statistical significant decrease in the SN+ experiments, while skin blood circulation was hardly effected in the SN- experiments. It is concluded that the use of smokeless tobacco in the form of oral use of snus containing nicotine causes a decrease in peripheral skin blood circulation while such an effect is not seen in snus without nicotine. This knowledge may be of use when treating patients that require adequate peripheral skin circulation or in the military when soldiers are exposed cold conditions.

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