{"title":"最终结果:IL-2对hiv感染患者没有益处。白细胞介素-2可以改善接受抗逆转录病毒治疗的患者的cd4细胞恢复,但这种益处并不能降低患病或死亡的风险。","authors":"Charles B Hicks","doi":"10.1056/AC201001040000006","DOIUrl":null,"url":null,"abstract":"For years, researchers have tried to find ways to incorporate interleukin (IL)-2 into HIV management, given its positive effects on CD4-cell counts. However, two large trials this year — SILCAAT and ESPRIT — demonstrated that those positive effects do not translate into …","PeriodicalId":88277,"journal":{"name":"Journal watch. AIDS clinical care","volume":"3 1","pages":"4"},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Definitive results: IL-2 does not benefit HIV-infected patients. Interleukin-2 improves CD4-cell recovery in patients on antiretroviral therapy, but that benefit does not translate into lower risks for disease or death.\",\"authors\":\"Charles B Hicks\",\"doi\":\"10.1056/AC201001040000006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"For years, researchers have tried to find ways to incorporate interleukin (IL)-2 into HIV management, given its positive effects on CD4-cell counts. However, two large trials this year — SILCAAT and ESPRIT — demonstrated that those positive effects do not translate into …\",\"PeriodicalId\":88277,\"journal\":{\"name\":\"Journal watch. AIDS clinical care\",\"volume\":\"3 1\",\"pages\":\"4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal watch. AIDS clinical care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1056/AC201001040000006\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal watch. AIDS clinical care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1056/AC201001040000006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Definitive results: IL-2 does not benefit HIV-infected patients. Interleukin-2 improves CD4-cell recovery in patients on antiretroviral therapy, but that benefit does not translate into lower risks for disease or death.
For years, researchers have tried to find ways to incorporate interleukin (IL)-2 into HIV management, given its positive effects on CD4-cell counts. However, two large trials this year — SILCAAT and ESPRIT — demonstrated that those positive effects do not translate into …