药师在自闭症谱系障碍管理中的作用:一项调查,以确定家长的知识和认知

Zeliha Pala Kara, B. Cakir, Deniz Kaleli Durman, B. Uydeş Doğan
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引用次数: 0

摘要

背景和目的:自闭症谱系障碍(ASD)是儿童神经精神疾病之一,有许多原因,包括遗传、神经生物学、环境以及其他可能引发该疾病的风险因素。这项调查的目的是确定家庭对自闭症谱系障碍的了解程度,最常用的处方药,它们的副作用以及除了药物治疗之外使用的替代疗法。方法:本研究以问卷调查为基础,对50例ASD患儿家长进行调查。结果:利培酮、阿立哌唑和丙戊酸是处方最多的药物(64%),主要副作用为体重增加(n=14)、攻击行为增加(n=11)和嗜睡/镇静(n=11)。除药物治疗外,大多数ASD儿童还使用了补充和替代药物,如无麸质和酪蛋白饮食(n= 23)或无糖饮食(n=15),以及omega-3 (n=43)、多种维生素(n=40)、重金属螯合剂(n=27)、维生素B12 (n=18)、锌(n=17)、维生素D (n=9)和益生菌(n= 7)。提示药师应向家长介绍自闭症的一般特征,向家长介绍新的治疗方法,并为自闭症儿童合理使用处方药提供建议。您可以将本文引用为:Pala Kara Z, Cakir B, Kaleli Durman D, Uydes Dogan S(2019)。药师在自闭症谱系障碍管理中的作用:一项调查,以确定家长的知识和认知。IstanbulJPharm 10.26650/ istanbuljpharma .2019.19042。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of pharmacists in the management of autism spectrum disorder: A survey to determine the knowledge and perception of the parents
DOI : 10.26650/IstanbulJPharm.2019.19042 Background and aims : Autism spectrum disorder (ASD) is one of the neuropsychiatric disorders of childhood and has many causes including genetic, neurobiological, environmental as well as other risk factors that can trigger the disorder. The aim of this survey is to determine the knowledge of the families about ASD, the most prescribed medications, their side effects and the alternative therapies used besides to the pharmacological treatment. Methods : This study was survey-based and conducted among parents of children with ASD (N=50). Results : Risperidone, aripiprazole, and valproate were the most prescripted drugs (64%) and weight gain (n=14), increased aggressive behavior (n=11) and drowsiness/sedation (n=11) were reported as the main side effects. Besides to pharmacological therapy, most of ASD children have used complementary and alternative medicine like gluten and casein-free diet (n =23) or the sugar diet (n=15) as well as omega-3 (n=43), multivitamins (n=40), heavy metal chelation agents (n=27), vitamin B12 (n=18), zinc (n=17) vitamin D (n=9), and probiotics (n= 7). Conclusion : It is revealed that pharmacists should be able to inform the parents about the general characteristics of ASD, to inform the parents about new treatment approaches and providing rational use of prescribed drugs in children with autism. You may cite this article as : Pala Kara Z, Cakir B, Kaleli Durman D, Uydes Dogan S (2019). The role of pharmacists in the management of autism spectrum disorder: A survey to determine the knowledge and perception of the parents. Istanbul J Pharm 10.26650/IstanbulJPharm.2019.19042.
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