太赫兹超材料检测人类肿瘤标志物

2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) Pub Date : 2018-09-01 DOI:10.1109/IRMMW-THZ.2018.8510052

C. Weisenstein, D. Schaar, M. Schmeck, A. Wigger, Anja Bosserhoff, P. Bolívar

{"title":"太赫兹超材料检测人类肿瘤标志物","authors":"C. Weisenstein, D. Schaar, M. Schmeck, A. Wigger, Anja Bosserhoff, P. Bolívar","doi":"10.1109/IRMMW-THZ.2018.8510052","DOIUrl":null,"url":null,"abstract":"THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.","PeriodicalId":6653,"journal":{"name":"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)","volume":"18 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Detection of Human Tumor Markers with THz Metamaterials\",\"authors\":\"C. Weisenstein, D. Schaar, M. Schmeck, A. Wigger, Anja Bosserhoff, P. Bolívar\",\"doi\":\"10.1109/IRMMW-THZ.2018.8510052\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.\",\"PeriodicalId\":6653,\"journal\":{\"name\":\"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)\",\"volume\":\"18 1\",\"pages\":\"1-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IRMMW-THZ.2018.8510052\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IRMMW-THZ.2018.8510052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 4

摘要

太赫兹生物分析技术已经被证明是一种可行的无标记检测生物分子的工具。但是，太赫兹传感技术要达到与应用相关的灵敏度水平，还需要进行重大改进。我们提出了使用高度敏感的超材料基太赫兹生物传感器对人类肿瘤标志物进行无标记太赫兹传感。利用特异性蛋白与DNA的高亲和力结合进行定位功能化，进一步提高检测灵敏度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Detection of Human Tumor Markers with THz Metamaterials

THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)

自引率

0.00%

发文量