流行性腮腺炎传播的数学模型及其最优控制

Emmanuel Chidiebere Duru, M. Anyanwu
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引用次数: 1

摘要

腮腺炎是一种病毒性传染病,伴有面颊肿胀和下颚肿胀。它通过直接接触感染者口、鼻或喉咙的唾液或呼吸道飞沫传播。在这项工作中,我们提出了一个数学模型来描述这种疾病在人群中的动态。该模型将隔离和治疗受感染个体作为一种控制措施。结果表明,当控制繁殖数Rc小于1时,无病平衡点(DFE)是局部和全局渐近稳定的。当Rc > 1时,该模型存在唯一的地方性平衡。唯一地方性平衡的存在证实了DFE的全局稳定性和模型不存在后向分叉。对模型进行最优控制分析,得到需要隔离的感染者比例,以实现疾病的最优控制。图中显示了在采取控制措施的情况下疾病的动态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mathematical model for the transmission of mumps and its optimal control
Summary Mumps is a viral contagious disease associated with puffy cheeks and tender and swollen jaw. It spreads through direct contact with saliva or respiratory droplets from the mouth, nose or throat of infected persons. In this work, we present a mathematical model which describes the dynamics of the disease in a human population. The model incorporates isolation and treatment of infected individuals as a control measure. It is shown that the disease-free equilibrium (DFE) is locally and globally asymptotically stable when the control reproduction number Rc is less than one. It is also shown that the model has a unique endemic equilibrium which exists when Rc > 1. The existence of a unique endemic equilibrium confirms the global stability of the DFE, and the absence of backward bifurcation in the model. Optimal control analysis is performed on the model to obtain the proportion of infected humans to be isolated for optimal control of the disease. Plots are presented to show the dynamics of the disease in the presence of the control measures.
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