男性生殖欲望顾问的流行-临床和精液概况:刚果民主共和国卢本巴希的情况

IF 0.9 3区 生物学 Q3 MARINE & FRESHWATER BIOLOGY
International Review of Hydrobiology Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI:10.11604/pamj.2023.45.177.36977
Jean Jimmy Kalfando Mwamba, Olivier Mukuku, Kumelundu Kasongo, Herman Kitoko Tamubango, Cynthia Mwenya Kibwe, Ignace Nday Tshikala, Jeannot Bakajika Kabue, Jean-Paul Nkenga Ilunga, Philémon Matumo Mumbere, Rivain Fefe Iteke, Joseph Bulanda Nsambi, Prosper Luhete Kakudji, Xavier Kalume Kinenkinda, Jean-Baptiste Kakoma
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引用次数: 0

摘要

简介:在卢本巴希,就像在生育探索非常聪明的高档地区一样,精子图仍然是诊断男性不育症的基本分析。这是40%的夫妇不孕的原因。精子图是鉴别精子异常的第一步。本研究的目的是确定卢本巴希求诊的男性的流行病学-临床和精液概况。方法:采用横断面研究。我们在卢本巴希接收了202名受试者,于2020年8月1日至2021年7月31日进行了精子涂片。根据世卫组织标准(2010年)对精液参数进行了研究和解释,并研究了与其干扰相关的因素。进行了双变量和多变量分析。差异有统计学意义,p < 0.05。结果:受访者的流行病学-临床概况如下:最具代表性的年龄组为30至39岁;80.69%为原发性不孕症;亲子愿望持续时间最长为2年,占44.55%。精子异常分别为少精症(40.09%)、无精症(11.38%)、弱精症(18.31%)和畸形精症(10.39%)。少精症与精索静脉曲张显著相关(ORa = 10.9 [3.0-39.5];p < 0.0001),生殖器感染(ORa =2.7 [1.0- 7,2];p = 0.041)和肥胖(ORa = 2.6 [1.0-7.9];p = 0.020),无精子症治疗腹股沟疝(ORa = 4.2 [1.0-17.2];p = 0.049)和营养不良(ORa =6.0 [1.2-29.7];P = 0.027)。弱精子症与40 ~ 49岁年龄组显著相关(ORa = 6.6 [1.2 ~ 37.4];p = 0.034),烟草(ORa =7.5 [2.7 -21.0];p = 0.000),营养不良(ORa = 7.7 [1.0-61.9];p = 0.045)和超重(ORa =3.8 [1.3- 11,5];p = 0.019)。畸形精子症与吸烟显著相关(ORa = 5.6 [1.8-17.7];p = 0.003)和超重(ORa =5.3 [1.2-23.3];P = 0.027)。结论:在三个主要生育参数中,超过一半的受访者至少有一个受到干扰。精子数是受影响最大的参数。酒精、烟草、生殖器感染和营养不良是观察到的异常情况最常见的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Epidemio-clinical and seminal profile of the man consulting for the desire to procreate: current situation in Lubumbashi, in the Democratic Republic of Congo].

Introduction: in Lubumbashi, as in upscale areas where explorations of fertility are very clever, the spermogram remains the essential analysis in the diagnosis of male infertility. This is the cause of 40% of couple infertility. The spermogram is the first step in identifying seminal abnormalities. The objective of this study was to determine the epidemiological-clinical and seminal profile of the man consulting for the desire to procreate in Lubumbashi.

Methods: this was a cross-sectional study. We received 202 subjects in Lubumbashi, whose spermogram was performed from August 1st, 2020 to July 31st, 2021. The semen parameters were studied and interpreted according to WHO standards (2010) with studies of factors associated with their disturbance. Bivariate and multivariate analyzes had been carried out. The statistical significance threshold was set at p < 0.05.

Results: the epidemiological-clinical profile of the respondents was as follows: the most represented age group was 30 to 39 years; infertility was primary in 80.69% of cases; the duration of the desire for paternity was 2 years at most in 44.55% of cases. The sperm abnormalities found were: oligozoospermia (40.09%), azoospermia (11.38%), asthenozoospermia (18.31%) and teratozoospermia (10.39%). Oligozoospermia was significantly associated with varicocele (ORa = 10.9 [3.0-39.5]; p < 0.0001), genital infection (ORa =2.7 [1.0-7, 2]; p = 0.041) and obesity (ORa = 2.6 [1.0-7.9]; p = 0.020) while azoospermia was the cure for inguinal hernia (ORa = 4.2 [1.0-17.2]; p = 0.049) and malnutrition (ORa =6.0 [1.2-29.7]; p = 0.027). Asthenozoospermia was significantly associated with the age group of 40 to 49 years (ORa = 6.6 [1.2-37.4]; p = 0.034), tobacco (ORa =7.5 [2.7 -21.0]; p = 0.000), undernutrition (ORa = 7.7 [1.0-61.9]; p = 0.045) and overweight (ORa =3.8 [1.3-11, 5]; p=0.019). Teratozoospermia was significantly associated with smoking (ORa = 5.6 [1.8-17.7]; p = 0.003) and overweight (ORa =5.3 [1.2-23.3]; p = 0.027).

Conclusion: more than half of the respondents had, of the three main fertility parameters, at least one that was disturbed. Sperm count was the most affected parameter. Alcohol, tobacco, genital infection and malnutrition were the most common risk factors for the abnormalities observed.

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来源期刊
International Review of Hydrobiology
International Review of Hydrobiology 生物-海洋与淡水生物学
CiteScore
4.10
自引率
10.50%
发文量
15
审稿时长
3 months
期刊介绍: As human populations grow across the planet, water security, biodiversity loss and the loss of aquatic ecosystem services take on ever increasing priority for policy makers. International Review of Hydrobiology brings together in one forum fundamental and problem-oriented research on the challenges facing marine and freshwater biology in an economically changing world. Interdisciplinary in nature, articles cover all aspects of aquatic ecosystems, ranging from headwater streams to the ocean and biodiversity studies to ecosystem functioning, modeling approaches including GIS and resource management, with special emphasis on the link between marine and freshwater environments. The editors expressly welcome research on baseline data. The knowledge-driven papers will interest researchers, while the problem-driven articles will be of particular interest to policy makers. The overarching aim of the journal is to translate science into policy, allowing us to understand global systems yet act on a regional scale. International Review of Hydrobiology publishes original articles, reviews, short communications, and methods papers.
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