G. Falchook, J. Glass, V. Monga, P. Giglio, D. Mauro, J. Viscusi, P. Scherle, N. Bhagwat, William Sun, R. Chiaverelli, Eric Mintah, L. Clements, T. Johanns, M. McKean
{"title":"P044:蛋白精氨酸甲基转移酶5 (PRMT5)脑渗透抑制剂PRT811在晚期实体瘤(包括复发性高级别胶质瘤)患者中的一期剂量递增研究","authors":"G. Falchook, J. Glass, V. Monga, P. Giglio, D. Mauro, J. Viscusi, P. Scherle, N. Bhagwat, William Sun, R. Chiaverelli, Eric Mintah, L. Clements, T. Johanns, M. McKean","doi":"10.1158/1535-7163.targ-21-p044","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"11 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Abstract P044: A phase 1 dose escalation study of protein arginine methyltransferase 5 (PRMT5) brain penetrant inhibitor PRT811 in patients with advanced solid tumors, including recurrent high-grade gliomas\",\"authors\":\"G. Falchook, J. Glass, V. Monga, P. Giglio, D. Mauro, J. Viscusi, P. Scherle, N. Bhagwat, William Sun, R. Chiaverelli, Eric Mintah, L. Clements, T. Johanns, M. McKean\",\"doi\":\"10.1158/1535-7163.targ-21-p044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":20348,\"journal\":{\"name\":\"Poster Presentations - Proffered Abstracts\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Poster Presentations - Proffered Abstracts\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1158/1535-7163.targ-21-p044\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Poster Presentations - Proffered Abstracts","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1158/1535-7163.targ-21-p044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Abstract P044: A phase 1 dose escalation study of protein arginine methyltransferase 5 (PRMT5) brain penetrant inhibitor PRT811 in patients with advanced solid tumors, including recurrent high-grade gliomas