成人双相情感障碍患者丙戊酸盐诱发急性胰腺炎的罕见并发症:1例报告

Prabhjot Kaur, D. Bhasin, T. S. Kundra
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引用次数: 0

摘要

背景:丙戊酸诱发的胰腺炎是一种特殊的药物反应,常见于儿科年龄组,在开始使用该药的1周到8年之间。病例:作者提出了一个病例报告的61岁的病人谁提出了急性胰腺炎。排除了所有共同原因。患者有服用丙戊酸酯治疗双相情感障碍12年的显著治疗史。病人通过静脉输液和止痛剂复苏。停用丙戊酸钠。对患者进行监测,以发现系统性炎症反应综合征或任何器官功能障碍或衰竭的早期症状。4天后,病人被送进病房。由于早期诊断和复苏,患者预后良好。结论:急性胰腺炎是丙戊酸钠治疗患者中一种罕见且可能致命的并发症。在排除其他常见原因后,详细的医疗和治疗历史可导致该实体的诊断。医疗保健提供者应警惕胰腺炎的早期症状和体征,包括急腹症、呕吐、血清淀粉酶和脂肪酶升高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Complication of Valproate-Induced Acute Pancreatitis in an Adult Patient with Bipolar Disorder: A Case Report
Background: Valproate-induced pancreatitis is an idiosyncratic reaction of the drug, commonly seen in the paediatric age group, between 1 week to 8 years of starting the drug. Case: The authors present a case report of a 61-year-old patient who presented with acute pancreatitis. All common causes were ruled out. The patient had a significant treatment history of taking valproate for bipolar disorder for 12 years. The patient was resuscitated with intravenous fluids and analgesics. Sodium valproate was stopped. The patient was monitored to detect early symptoms of systemic inflammatory response syndrome or any organ dysfunction or failure. The patient was sent to the ward after 4 days. The patient had a good outcome due to early diagnosis and resuscitation. Conclusion: Acute pancreatitis is a rare and potentially fatal complication in patients on valproate. After ruling out other common causes, a detailed medical and treatment history can lead to the diagnosis of this entity. Healthcare providers should be vigilant about the early signs and symptoms of pancreatitis, including acute abdomen, vomiting, and raised serum amylase and lipase.
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