Clinical evaluation of acellular dermal matrix allograft (Alloderm®) with coronally advanced flap in the treatment of multiple gingival recessions: A clinical study

Aims: The purpose of this study was to clinically evaluate the efficacy of Alloderm® with the coronally positioned flap in the treatment of multiple gingival recessions and to assess the esthetic and hypersensitivity evaluation from patient's perspective using visual analog scale (VAS). Subjects and Methods: A total of 10 systemically healthy male and female patients aged 18–50 years with Miller's class I and class II gingival recessions, who had dentin hypersensitivity and esthetic concern were selected for the study. Root coverage (RC) was done using coronally advanced flap with Alloderm®. Statistical Analysis: Descriptive statistical analysis was performed in the present study. Significance was assessed at 5% level of significance. Student's t-test was conducted to find the pairwise significance of the study parameters. Wilcoxon signed-rank test was used to find the significance of percentage of linear RC and percentage of volumetric RC (% of VRC) between 3 and 6 months. Results: A total 31 defects were treated with mean volumetric percentage RC (%RC) at 3 months of 35.21%. This remained the same at 6 months (P = 1.000). There was no statistically significant difference in the volumetric and Linear percentage of root coverage. Dentine hypersensitivity and esthetics were evaluated from patient's perspective using VAS ranging from a score of 0–10. Where 0 indicates very low and score of 10 indicates very high score. VAS indicated a decrease in the sensitivity after treatment. VAS mean score before treatment was 6.22 ± 0.83 with a mean score of 3.90, standard deviation (SD) of ± 1.37 after treatment and mean score of 5.10, SD of ± 0.57 for esthetic evaluation. Conclusions: The use of Alloderm® with coronally positioned flap provided a significant improvement in all the clinical parameters, but did not result in favorable outcome in terms of root coverage of facial gingival recessions of multiple adjacent teeth.