新科与生物技术疫苗接种对重症监护病房COVID-19患者死亡率的影响

Q4 Medicine
Ülkü İnce, Harun Duran, Y. Yıldırım
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引用次数: 0

摘要

导语:COVID-19感染随着大流行的发展而传播,并通过呼吸道飞沫传播。与COVID-19疫苗一起接种的疫苗的保护水平是研究的主题。我们的目的是检查重症监护患者使用科兴和Biontech疫苗。材料和方法:经伦理委员会批准,45例患者资料纳入我们的研究。对重症监护病房的疫苗接种情况进行了检查,并将患者分为科兴和Biontech两组。年龄、性别、合并症和死亡率进行统计学比较。通过比较,评估对死亡率和临床特征的影响。结果:45例患者于2021年3月31日至12月31日纳入研究。在这些患者中,根据重症监护评估标准对住院前接受2剂疫苗接种的患者进行检查。在重症监护病房住院的患者中,接受两剂科兴疫苗的患者死亡率高于接受两剂Biontech疫苗的患者。结论:观察到接种COVID-19疫苗并进入重症监护病房的患者的疫苗接种状况影响死亡率。需要对大量患者进行研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Sinovac or Biontech Vaccination on Mortality in COVID-19 Patients in The Intensive Care Unit
Introduction: COVID-19 infection has spread with the development of the pandemic and is transmitted by respiratory droplets. The level of protection of vaccines administered together with the COVID-19 vaccine is the subject of research. We aimed to examine intensive care patients with Sinovac and Biontech vaccines. Material and Method: After the approval of the ethics committee, 45 patient data were included in our study. Vaccination status in intensive care units was examined and patients were grouped into Sinovac and Biontech. Age, sex, comorbid conditions, and mortality rates were compared statistically. With this comparison, the effects on mortality and clinical features were evaluated. Results: Forty-five patients between March 31 and December 31, 2021 were included in the study. In these patients, patients who received 2 doses of vaccine in the period before hospitalization according to the intensive care evaluation criteria were examined. Mortality rates were higher in patients who received 2 doses of Sinovac vaccine in patients hospitalized in the intensive care unit compared to those who received 2 doses of Biontech vaccine. Conclusion: It was observed that the vaccination status of patients who were vaccinated with COVID-19 and taken to the intensive care unit affected mortality. Studies with larger numbers of patients are needed.
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