肝细胞癌在专科外科中心的切除干预治疗

Q4 Immunology and Microbiology
V. Pelts, V. E. Tropin, V. A. Shatalin
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引用次数: 0

摘要

背景。肝细胞癌(HCC)治疗的相关性是由原发性恶性肝肿瘤的发病率显著增加和高患病率决定的。研究的目的。目的总结为肝癌患者提供专科医疗护理的经验。我们研究了2015年1月至2022年8月期间在库兹巴斯地区肝病中心治疗的原发性肝癌患者的直接治疗结果。本研究的资料为确诊为原发性肝癌的患者的医疗记录、手术记录、病理组织学检查结果。排除标准为胆管细胞癌。2015年至2022年期间,59名原发性肝癌患者在库兹巴斯地区肝病中心接受了治疗。其中肝细胞癌48例,胆管细胞癌11例;12例肝细胞癌行根治性手术;死亡1例(2.1%),术后出现并发症5例(41.7%),按Clavien - Dindo分级分为I-3、iib -1和IVb-1。术后发生严重肝功能衰竭的风险程度应作为选择根治性手术治疗策略的主要标准之一。在原发性肝癌切除手术中采用新的手术入路(腹腔镜门静脉血流血管隔离、腹腔镜肝切除术采用临时止血术及其实施装置)可提高治疗的立竿见影效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Resection interventions in the treatment of hepatocellular cancer in a specialized surgery center
Background. The relevance of the treatment of hepatocellular cancer (HCC) is determined by a significant increase in the incidence rate and its high prevalence among primary malignant hepatic tumors.The aim of the study. To summarize the experience of providing specialized medical care to patients with hepatocellular cancer.Methods. We studied the direct results of treatment of patients with primary hepatic cancer treated at the Kuzbass Regional Hepatological Center for the period from January 2015 to August 2022. The materials for the study were medical records of patients with an established diagnosis of primary hepatic cancer, surgical records, results of pathohistologic examination. The exclusion criterion was diagnosed cholangiocellular carcinoma.Results. During the period from 2015 to 2022, 59 patients with primary hepatic cancer were treated at the Kuzbass Regional Hepatological Center. Among them, hepatocellular cancer was diagnosed in 48 cases, cholangiocellular cancer – in 11 cases; radical surgery was performed in 12 patients with hepatocellular cancer; fatal outcome was noted in 1 (2.1 %) patient, complications in the postoperative period developed in 5 (41.7 %) cases and were ranked as I-3, IIIb-1 and IVb-1 according to Clavien – Dindo classification.Conclusion. The degree of risk of severe post-resection hepatic failure should be considered one of the main criteria in choosing a strategy for radical surgical treatment. New surgical approaches (laparoscopic vascular isolation of the portal blood flow, using temporary hemostasis in laparoscopic hepatic resections and the device for its implementation) in resection surgery of primary hepatic cancer can improve the immediate results of treatment.
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来源期刊
Acta Biomedica Scientifica
Acta Biomedica Scientifica Immunology and Microbiology-General Immunology and Microbiology
CiteScore
0.40
自引率
0.00%
发文量
106
审稿时长
7 weeks
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