Quantum correction of homeostatic disorders in patients with mechanical jaundice

Purpose. To study the effectiveness of low-level laser therapy (LLLT) for the correction of homeostatic disorders in severe mechanical jaundice of non-tumor origin at the early postoperative period. Material and methods. The authors present their results of treating 45 patients with mechanical jaundice (MJ) of non-neoplastic genesis and of various severity. Patients were randomized into three groups: Group 1 (n = 15) – patients with mild MJ who were prescribed standard treatment at the postoperative period; Group 2 (n = 15) – patients with severe MJ who were also prescribed standard treatment; Group 3 (n = 15) – patients' state similar to that of Group 2 but who were added laser therapy sessions to their standard treatment. Laser «Matrix» was used for this. The intensity of lipoperoxidation processes, phospholipase activity, microcirculation, hemostasis and liver functional state were assessed. Results. It was found that at the early postoperative period (up to day 8), patients with mechanical jaundice of non-tumor genesis have marked deviations in homeostasis, like oxidative stress, activation of phospholipase system, microcirculatory disorders, hepatic dysfunction and hemostatic disorders, the severity of which is associated with the severity of pathology. The therapeutic effectiveness of basic treatment at early stages in patients with mild MJ was enough, while in patients with severe MJ not always. Conclusion. Supravascular quantum irradiation added to standard therapy in patients with severe mechanical jaundice promotes more rapid restoration of hepatic dysfunction and more effective correction of the homeostatic system.