大环聚醚和季铵盐促进SN2反应的溶剂效应

Dario Landini, Angelamaria Maia
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引用次数: 0

摘要

在不同极性的有机溶剂中,研究了溶剂对4NO2–C6H4O–和N3–[作为络合K+⊂(DCH18C6)或季鎓盐]在二烷基衍生物(nC4H9Yand nC8H17Y;Y=OMs,Br,I)中亲核取代反应速率的影响。结果表明,在烷基甲磺酸盐的情况下,反应速率通过降低介质的极性而逐渐增加,而对于卤代衍生物RHal(Hal=Br,I),仅在最极性的溶剂中观察到最高速率。这些数据是在基态和过渡态溶剂化的差异的基础上讨论的,这取决于离去基团的性质。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Solvent effects in SN2 reactions promoted by macrocyclic polyethers and quaternary onium salts
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