Annamalai Aravinth , Sundaramoorthy Dhanasundaram , Pachiappan Perumal , Chinnaperumal Kamaraj , Safir Ullah Khan , Amir Ali , Chinnasamy Ragavendran , Vadivel Amutha , Rajendran Rajaram , Perumal Santhanam , Juan Pedro Luna-Arias , Zia-ur-Rehman Mashwani
{"title":"棕色和红色海藻提取物作为一种新型杀幼虫剂对抗致命人类疾病媒介斯氏按蚊、埃及伊蚊和致倦库蚊的评价。","authors":"Annamalai Aravinth , Sundaramoorthy Dhanasundaram , Pachiappan Perumal , Chinnaperumal Kamaraj , Safir Ullah Khan , Amir Ali , Chinnasamy Ragavendran , Vadivel Amutha , Rajendran Rajaram , Perumal Santhanam , Juan Pedro Luna-Arias , Zia-ur-Rehman Mashwani","doi":"10.1016/j.exppara.2023.108651","DOIUrl":null,"url":null,"abstract":"<div><p>Infectious diseases such as malaria, dengue, and yellow fever are predominantly transmitted by insect vectors like <span><em>Anopheles stephensi</em><span><em>, </em><em>Aedes aegypti</em></span></span>, and <span><em>Culex quinquefasciatus</em></span> in tropical regions like India and Africa. In this study, we assessed the larvicidal activity of commonly found seaweeds, including <span><em>Padina gymnospora, P. pavonica, </em><em>Gracilaria</em><em> crassa, Amphiroa fragilissima</em></span>, and <em>Spatoglossum marginatum</em>, against these mosquito vectors. Our findings indicate that extracts from <em>P. gymnospora</em> Ethyl Acetate (PgEA), <em>P. pavonica Hexane</em> (PpH), and <em>A. fragilissima</em> Ethyl Acetate (AfEA) displayed the highest larval mortality rates for <em>A. stephensi</em>, with LC50 values of 10.51, 12.43, and 6.43 μg/mL, respectively. Additionally, the PgEA extract from <em>P. gymnospora</em> exhibited the highest mortality rate for <em>A. aegypti</em>, with an LC50 of 27.0 μg/mL, while the PgH extract from the same seaweed showed the highest mortality rate for <em>C. quinquefasciatus</em><span>, with an LC50 of 9.26 μg/mL. Phytochemical analysis of the seaweed extracts revealed the presence of 71 compounds in the solvent extracts. Fourier-transform infrared spectra of the selected seaweeds indicated the presence of functional groups such as alkanes, alcohols, and phenols. Gas chromatography–mass spectrometry analysis of the seaweeds identified major compounds, including hexadecanoic acid in PgEA, tetradecene (e)- in PpEA, octadecanoic acid in GcEA, and 7-hexadecene, (z)-, and trans-7-pentadecene in SmEA.</span></p></div>","PeriodicalId":12117,"journal":{"name":"Experimental parasitology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus\",\"authors\":\"Annamalai Aravinth , Sundaramoorthy Dhanasundaram , Pachiappan Perumal , Chinnaperumal Kamaraj , Safir Ullah Khan , Amir Ali , Chinnasamy Ragavendran , Vadivel Amutha , Rajendran Rajaram , Perumal Santhanam , Juan Pedro Luna-Arias , Zia-ur-Rehman Mashwani\",\"doi\":\"10.1016/j.exppara.2023.108651\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Infectious diseases such as malaria, dengue, and yellow fever are predominantly transmitted by insect vectors like <span><em>Anopheles stephensi</em><span><em>, </em><em>Aedes aegypti</em></span></span>, and <span><em>Culex quinquefasciatus</em></span> in tropical regions like India and Africa. In this study, we assessed the larvicidal activity of commonly found seaweeds, including <span><em>Padina gymnospora, P. pavonica, </em><em>Gracilaria</em><em> crassa, Amphiroa fragilissima</em></span>, and <em>Spatoglossum marginatum</em>, against these mosquito vectors. Our findings indicate that extracts from <em>P. gymnospora</em> Ethyl Acetate (PgEA), <em>P. pavonica Hexane</em> (PpH), and <em>A. fragilissima</em> Ethyl Acetate (AfEA) displayed the highest larval mortality rates for <em>A. stephensi</em>, with LC50 values of 10.51, 12.43, and 6.43 μg/mL, respectively. Additionally, the PgEA extract from <em>P. gymnospora</em> exhibited the highest mortality rate for <em>A. aegypti</em>, with an LC50 of 27.0 μg/mL, while the PgH extract from the same seaweed showed the highest mortality rate for <em>C. quinquefasciatus</em><span>, with an LC50 of 9.26 μg/mL. Phytochemical analysis of the seaweed extracts revealed the presence of 71 compounds in the solvent extracts. Fourier-transform infrared spectra of the selected seaweeds indicated the presence of functional groups such as alkanes, alcohols, and phenols. Gas chromatography–mass spectrometry analysis of the seaweeds identified major compounds, including hexadecanoic acid in PgEA, tetradecene (e)- in PpEA, octadecanoic acid in GcEA, and 7-hexadecene, (z)-, and trans-7-pentadecene in SmEA.</span></p></div>\",\"PeriodicalId\":12117,\"journal\":{\"name\":\"Experimental parasitology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-11-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimental parasitology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0014489423001923\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PARASITOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental parasitology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014489423001923","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PARASITOLOGY","Score":null,"Total":0}
Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus
Infectious diseases such as malaria, dengue, and yellow fever are predominantly transmitted by insect vectors like Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus in tropical regions like India and Africa. In this study, we assessed the larvicidal activity of commonly found seaweeds, including Padina gymnospora, P. pavonica, Gracilaria crassa, Amphiroa fragilissima, and Spatoglossum marginatum, against these mosquito vectors. Our findings indicate that extracts from P. gymnospora Ethyl Acetate (PgEA), P. pavonica Hexane (PpH), and A. fragilissima Ethyl Acetate (AfEA) displayed the highest larval mortality rates for A. stephensi, with LC50 values of 10.51, 12.43, and 6.43 μg/mL, respectively. Additionally, the PgEA extract from P. gymnospora exhibited the highest mortality rate for A. aegypti, with an LC50 of 27.0 μg/mL, while the PgH extract from the same seaweed showed the highest mortality rate for C. quinquefasciatus, with an LC50 of 9.26 μg/mL. Phytochemical analysis of the seaweed extracts revealed the presence of 71 compounds in the solvent extracts. Fourier-transform infrared spectra of the selected seaweeds indicated the presence of functional groups such as alkanes, alcohols, and phenols. Gas chromatography–mass spectrometry analysis of the seaweeds identified major compounds, including hexadecanoic acid in PgEA, tetradecene (e)- in PpEA, octadecanoic acid in GcEA, and 7-hexadecene, (z)-, and trans-7-pentadecene in SmEA.
期刊介绍:
Experimental Parasitology emphasizes modern approaches to parasitology, including molecular biology and immunology. The journal features original research papers on the physiological, metabolic, immunologic, biochemical, nutritional, and chemotherapeutic aspects of parasites and host-parasite relationships.