自身免疫性肝炎的治疗。

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Aparna Goel MD, Paul Kwo MD
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引用次数: 1

摘要

自身免疫性肝炎治疗的目标是实现临床和生化缓解,这与显著改善预后有关。皮质类固醇诱导治疗和随后增加的类固醇保留治疗,逐渐减少皮质类固醇仍然是护理的标准。硫唑嘌呤和二线药物的几种替代品,如霉酚酸酯、他克莫司、环孢菌素、西罗莫司或利妥昔单抗,已在对标准护理治疗不耐受或反应不足的患者中进行了评估。在持续缓解2年后,只有不到20%的患者可以停止治疗。对于进展性肝病或有肝细胞癌等并发症的患者,应考虑肝移植。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment of Autoimmune Hepatitis
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来源期刊
Clinics in liver disease
Clinics in liver disease GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.30
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: A perfect source to consult for those in the fields of gastroenterology and hepatology, Clinics in Liver Disease provides answers to clinical questions, information on the latest diagnostic methods and treatments, and numerous clinical images. Published quarterly—in February, May, August, and November—each issue offers in-depth reviews that focus on the liver and biliary system.
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