2023年睾丸癌症：现状和最新进展。

IF 503.1 1区医学 Q1 ONCOLOGY

CA: A Cancer Journal for Clinicians Pub Date : 2023-11-10 DOI:10.3322/caac.21819

Deaglan J. McHugh MD, Jack P. Gleeson MB BCh BAO, MRCPI, Darren R. Feldman MD

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引用次数: 0

摘要

睾丸生殖细胞瘤（GCT）是青少年和青年男性最常见的实体瘤。在过去的50年里，GCT的管理取得了进展，晚期疾病的治愈率从20世纪70年代的25%大幅提高到近80%。然而，复发或铂类难治性疾病在一定比例上发生，其中20%将死于疾病进展。本文综述了目前颅外GCT的循证治疗方法，可能产生的急性和慢性毒性作用，并强调了该领域的当代进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Testicular cancer in 2023: Current status and recent progress

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Testicular cancer in 2023: Current status and recent progress

Testicular germ cell tumor (GCT) is the most common solid tumor in adolescent and young adult men. Progress in the management of GCT has been made in the last 50 years, with a substantial improvement in cure rates for advanced disease, from 25% in the 1970s to nearly 80%. However, relapsed or platinum-refractory disease occurs in a proportion, 20% of whom will die from disease progression. This article reviews the current evidence-based treatments for extracranial GCT, the acute and chronic toxic effects that may result, and highlights contemporary advances and progress in the field.

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来源期刊

CA: A Cancer Journal for Clinicians 医学-肿瘤学

CiteScore

873.20

自引率

0.10%

发文量

审稿时长

1 months

期刊介绍： CA: A Cancer Journal for Clinicians" has been published by the American Cancer Society since 1950, making it one of the oldest peer-reviewed journals in oncology. It maintains the highest impact factor among all ISI-ranked journals. The journal effectively reaches a broad and diverse audience of health professionals, offering a unique platform to disseminate information on cancer prevention, early detection, various treatment modalities, palliative care, advocacy matters, quality-of-life topics, and more. As the premier journal of the American Cancer Society, it publishes mission-driven content that significantly influences patient care.