Hong Yang, Heng-Hui Zhang, Chang-Qing Li, Li-Jun Guo, Miao Yang, Tuo-Ping Hu
{"title":"两种基于双（吡唑）和羧酸共配体的银（I）配合物的合成、晶体结构和抗菌活性","authors":"Hong Yang, Heng-Hui Zhang, Chang-Qing Li, Li-Jun Guo, Miao Yang, Tuo-Ping Hu","doi":"10.1007/s11243-023-00556-5","DOIUrl":null,"url":null,"abstract":"<div><p>Two dinuclear and centrosymmetric silver-containing complexes, namely [Ag<sub>2</sub>(3,5-dmpz)<sub>2</sub>(3,5-dmpz methanol)<sub>2</sub>(tbtc)] (<b>1</b>) and [Ag<sub>2</sub>(3,5-dmpz)<sub>2</sub>(3,5-dmpz methanol)<sub>2</sub>(dbtc)] (<b>2</b>) (3,5-dmpz: dimethylpyrazole; 3,5-dmpz methanol: 3,5-dimethylpyrazole methanol; H<sub>2</sub>tbtc: tetrabromoterephthalic acid; H<sub>2</sub>dbtc: 2,5-dibromoterephthalic acid), were prepared and characterized. X-ray crystallographic data of <b>1</b> and <b>2</b> revealed that trigonal environment of the Ag ions has a “compressed Y’s” geometry. The antimicrobial activity of <b>1</b> and <b>2</b> was tested against the Gram-positive, Gram-negative bacteria and fungus, displaying the better inhibiting activity than the individual AgNO<sub>3</sub> and 3,5-dimethylpyrazole, especially for <i>Candida albicans</i> (IC<sub>50</sub> 2.5 ± 0.1 mg mL <sup>−1</sup> and 2.8 ± 0.2 mg mL<sup>−1</sup>). The quantified IC<sub>50</sub> values displayed that complexes <b>1</b> and <b>2</b> were more effective against fungus than the Gram-negative bacteria and Gram-positive bacteria.</p></div>","PeriodicalId":803,"journal":{"name":"Transition Metal Chemistry","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis, crystal structure and antimicrobial activities of two silver(I) complexes based on bis(pyrazole) and carboxylic acid co-ligands\",\"authors\":\"Hong Yang, Heng-Hui Zhang, Chang-Qing Li, Li-Jun Guo, Miao Yang, Tuo-Ping Hu\",\"doi\":\"10.1007/s11243-023-00556-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Two dinuclear and centrosymmetric silver-containing complexes, namely [Ag<sub>2</sub>(3,5-dmpz)<sub>2</sub>(3,5-dmpz methanol)<sub>2</sub>(tbtc)] (<b>1</b>) and [Ag<sub>2</sub>(3,5-dmpz)<sub>2</sub>(3,5-dmpz methanol)<sub>2</sub>(dbtc)] (<b>2</b>) (3,5-dmpz: dimethylpyrazole; 3,5-dmpz methanol: 3,5-dimethylpyrazole methanol; H<sub>2</sub>tbtc: tetrabromoterephthalic acid; H<sub>2</sub>dbtc: 2,5-dibromoterephthalic acid), were prepared and characterized. X-ray crystallographic data of <b>1</b> and <b>2</b> revealed that trigonal environment of the Ag ions has a “compressed Y’s” geometry. The antimicrobial activity of <b>1</b> and <b>2</b> was tested against the Gram-positive, Gram-negative bacteria and fungus, displaying the better inhibiting activity than the individual AgNO<sub>3</sub> and 3,5-dimethylpyrazole, especially for <i>Candida albicans</i> (IC<sub>50</sub> 2.5 ± 0.1 mg mL <sup>−1</sup> and 2.8 ± 0.2 mg mL<sup>−1</sup>). The quantified IC<sub>50</sub> values displayed that complexes <b>1</b> and <b>2</b> were more effective against fungus than the Gram-negative bacteria and Gram-positive bacteria.</p></div>\",\"PeriodicalId\":803,\"journal\":{\"name\":\"Transition Metal Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Transition Metal Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11243-023-00556-5\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transition Metal Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11243-023-00556-5","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Synthesis, crystal structure and antimicrobial activities of two silver(I) complexes based on bis(pyrazole) and carboxylic acid co-ligands
Two dinuclear and centrosymmetric silver-containing complexes, namely [Ag2(3,5-dmpz)2(3,5-dmpz methanol)2(tbtc)] (1) and [Ag2(3,5-dmpz)2(3,5-dmpz methanol)2(dbtc)] (2) (3,5-dmpz: dimethylpyrazole; 3,5-dmpz methanol: 3,5-dimethylpyrazole methanol; H2tbtc: tetrabromoterephthalic acid; H2dbtc: 2,5-dibromoterephthalic acid), were prepared and characterized. X-ray crystallographic data of 1 and 2 revealed that trigonal environment of the Ag ions has a “compressed Y’s” geometry. The antimicrobial activity of 1 and 2 was tested against the Gram-positive, Gram-negative bacteria and fungus, displaying the better inhibiting activity than the individual AgNO3 and 3,5-dimethylpyrazole, especially for Candida albicans (IC50 2.5 ± 0.1 mg mL −1 and 2.8 ± 0.2 mg mL−1). The quantified IC50 values displayed that complexes 1 and 2 were more effective against fungus than the Gram-negative bacteria and Gram-positive bacteria.
期刊介绍：
Transition Metal Chemistry is an international journal designed to deal with all aspects of the subject embodied in the title: the preparation of transition metal-based molecular compounds of all kinds (including complexes of the Group 12 elements), their structural, physical, kinetic, catalytic and biological properties, their use in chemical synthesis as well as their application in the widest context, their role in naturally occurring systems etc.
Manuscripts submitted to the journal should be of broad appeal to the readership and for this reason, papers which are confined to more specialised studies such as the measurement of solution phase equilibria or thermal decomposition studies, or papers which include extensive material on f-block elements, or papers dealing with non-molecular materials, will not normally be considered for publication. Work describing new ligands or coordination geometries must provide sufficient evidence for the confident assignment of structural formulae; this will usually take the form of one or more X-ray crystal structures.
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