Frank Hübner, Moritz Klaus, Norbert Siedow, Christian Leithäuser, Thomas Josef Vogl
{"title":"离体肾脏冷冻消融中组织扩张的CT评价。","authors":"Frank Hübner, Moritz Klaus, Norbert Siedow, Christian Leithäuser, Thomas Josef Vogl","doi":"10.1515/bmt-2023-0174","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate tissue expansion during cryoablation, the displacement of markers in <i>ex vivo</i> kidney tissue was determined using computed tomographic (CT) imaging.</p><p><strong>Methods: </strong>CT-guided cryoablation was performed in nine porcine kidneys over a 10 min period. Markers and fiber optic temperature probes were positioned perpendicular to the cryoprobe shaft in an axial orientation. The temperature measurement was performed simultaneously with the acquisitions of the CT images in 5 s intervals. The distance change of the markers to the cryoprobe was determined in each CT image and equated to the measured temperature at the marker.</p><p><strong>Results: </strong>The greatest increase in the distance between the markers and the cryoprobe was observed in the initial phase of cryoablation. The maximum displacement of the markers was determined to be 0.31±0.2 mm and 2.8±0.02 %, respectively.</p><p><strong>Conclusions: </strong>The mean expansion of <i>ex vivo</i> kidney tissue during cryoablation with a single cryoprobe is 0.31±0.2 mm. The results can be used for identification of basic parameters for optimization of therapy planning.</p>","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"211-217"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CT-based evaluation of tissue expansion in cryoablation of <i>ex vivo</i> kidney.\",\"authors\":\"Frank Hübner, Moritz Klaus, Norbert Siedow, Christian Leithäuser, Thomas Josef Vogl\",\"doi\":\"10.1515/bmt-2023-0174\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To evaluate tissue expansion during cryoablation, the displacement of markers in <i>ex vivo</i> kidney tissue was determined using computed tomographic (CT) imaging.</p><p><strong>Methods: </strong>CT-guided cryoablation was performed in nine porcine kidneys over a 10 min period. Markers and fiber optic temperature probes were positioned perpendicular to the cryoprobe shaft in an axial orientation. The temperature measurement was performed simultaneously with the acquisitions of the CT images in 5 s intervals. The distance change of the markers to the cryoprobe was determined in each CT image and equated to the measured temperature at the marker.</p><p><strong>Results: </strong>The greatest increase in the distance between the markers and the cryoprobe was observed in the initial phase of cryoablation. The maximum displacement of the markers was determined to be 0.31±0.2 mm and 2.8±0.02 %, respectively.</p><p><strong>Conclusions: </strong>The mean expansion of <i>ex vivo</i> kidney tissue during cryoablation with a single cryoprobe is 0.31±0.2 mm. The results can be used for identification of basic parameters for optimization of therapy planning.</p>\",\"PeriodicalId\":93905,\"journal\":{\"name\":\"Biomedizinische Technik. Biomedical engineering\",\"volume\":\" \",\"pages\":\"211-217\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedizinische Technik. Biomedical engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/bmt-2023-0174\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/4/25 0:00:00\",\"PubModel\":\"Print\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedizinische Technik. Biomedical engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/bmt-2023-0174","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/25 0:00:00","PubModel":"Print","JCR":"","JCRName":"","Score":null,"Total":0}
CT-based evaluation of tissue expansion in cryoablation of ex vivo kidney.
Objectives: To evaluate tissue expansion during cryoablation, the displacement of markers in ex vivo kidney tissue was determined using computed tomographic (CT) imaging.
Methods: CT-guided cryoablation was performed in nine porcine kidneys over a 10 min period. Markers and fiber optic temperature probes were positioned perpendicular to the cryoprobe shaft in an axial orientation. The temperature measurement was performed simultaneously with the acquisitions of the CT images in 5 s intervals. The distance change of the markers to the cryoprobe was determined in each CT image and equated to the measured temperature at the marker.
Results: The greatest increase in the distance between the markers and the cryoprobe was observed in the initial phase of cryoablation. The maximum displacement of the markers was determined to be 0.31±0.2 mm and 2.8±0.02 %, respectively.
Conclusions: The mean expansion of ex vivo kidney tissue during cryoablation with a single cryoprobe is 0.31±0.2 mm. The results can be used for identification of basic parameters for optimization of therapy planning.
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